Journal Article

PUBDB-2024-00573

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png New opportunities in integrative structural modeling

Ziemianowicz, D.CSSB*EMBL* ; Kosinski, J. (Corresponding author)CSSB*

2022
Elsevier Amsterdam [u.a.]

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Please use a persistent id in citations: doi:10.1016/j.sbi.2022.102488  doi:10.3204/PUBDB-2024-00573

Abstract: Integrative structural modeling enables structure determination of macromolecules and their complexes by integrating data from multiple sources. It has been successfully used to characterize macromolecular structures when a single structural biology technique was insufficient. Recent developments in cellular structural biology, including in-cell cryo-electron tomography and artificial intelligence-based structure prediction, have created new opportunities for integrative structural modeling. Here, we will review these opportunities along with the latest developments in integrative modeling methods and their applications. We also highlight open challenges and directions for further development.

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Contributing Institute(s):

1. CSSB-EMBL-JK (CSSB-EMBL-JK)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)
2. EIPOD4 - EMBL Interdisciplinary Postdoc Programme 4 (847543) (847543)

Experiment(s):

1. No specific instrument

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Database coverage:
; ; ; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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