TY  - JOUR
AU  - Ziemianowicz, Daniel
AU  - Kosinski, Jan
TI  - New opportunities in integrative structural modeling
JO  - Current opinion in structural biology
VL  - 77
SN  - 0959-440X
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - PUBDB-2024-00573
SP  - 102488 
PY  - 2022
AB  - Integrative structural modeling enables structure determination of macromolecules and their complexes by integrating data from multiple sources. It has been successfully used to characterize macromolecular structures when a single structural biology technique was insufficient. Recent developments in cellular structural biology, including in-cell cryo-electron tomography and artificial intelligence-based structure prediction, have created new opportunities for integrative structural modeling. Here, we will review these opportunities along with the latest developments in integrative modeling methods and their applications. We also highlight open challenges and directions for further development. 
LB  - PUB:(DE-HGF)16
C6  - pmid:36279817
UR  - <Go to ISI:>//WOS:000880116000002
DO  - DOI:10.1016/j.sbi.2022.102488
UR  - https://bib-pubdb1.desy.de/record/602298
ER  -