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000602298 1001_ $$0P:(DE-H253)PIP1093834$$aZiemianowicz, Daniel$$b0
000602298 245__ $$aNew opportunities in integrative structural modeling
000602298 260__ $$aAmsterdam [u.a.]$$bElsevier$$c2022
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000602298 520__ $$aIntegrative structural modeling enables structure determination of macromolecules and their complexes by integrating data from multiple sources. It has been successfully used to characterize macromolecular structures when a single structural biology technique was insufficient. Recent developments in cellular structural biology, including in-cell cryo-electron tomography and artificial intelligence-based structure prediction, have created new opportunities for integrative structural modeling. Here, we will review these opportunities along with the latest developments in integrative modeling methods and their applications. We also highlight open challenges and directions for further development. 
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000602298 7001_ $$0P:(DE-H253)PIP1081584$$aKosinski, Jan$$b1$$eCorresponding author
000602298 773__ $$0PERI:(DE-600)2019233-2$$a10.1016/j.sbi.2022.102488$$gVol. 77, p. 102488 -$$p102488 $$tCurrent opinion in structural biology$$v77$$x0959-440X$$y2022
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