VH-VI-403

In-Situ Nano-Imaging of Biological and Chemical Processes

CoordinatorSchroer, Christian ; Weckert, Edgar
Grant period2011-2016
Funding bodyHelmholtz Gemeinschaft Deutscher Forschungszentren
 HGF
IdentifierG:(DE-HGF)2015_IFV-VH-VI-403

Impuls- und Vernetzungsfonds

Note: In the emerging fields of nano science, chemical technology and the life sciences there is an increasing demand for imaging of micro- to nanometer sized objects with highest possible spatial resolution. The physical, chemical, and biological properties of nano-sized objects strongly depend on their structure. Therefore, nanoscopic structure determination is at the heart of understanding biological and chemical processes and is crucial to address the grand challenges in health, environmental, and energy research. X-ray imaging techniques are well suited to these ends, as they provide element specific chemical and structural contrast at high spatial resolution also from the interior of bulk samples or from samples in special environments. The new sources at DESY, PETRA III and FLASH, are ideal to reach these goals. In particular X-ray imaging techniques on the nanoscale directly benefit from the high brilliance of theses sources. In the frame of this Virtual Institute we would like to bring together expertise in x-ray imaging, biology and chemistry to enable in-situ imaging of biological and chemical processes with the xray microscopes at PETRA III and FLASH, and at the European XFEL in the future. In example applications, we will address important questions in biology (membranes, cell ultrastructure, selfassembly mechanisms) and chemistry (catalysis, redox and precipitation reactions), adapting and developing further the x-ray microscopes and special sample environments, such as chemical reactors, microfluidic cells and cryogenic sample environments. Our Virtual Institute comprises groups from four universities (U. Göttingen, U. Heidelberg, KIT Campus South, and TU Dresden) and DESY. The dual affiliation of two scientists to KIT Campus North also brings this Helmholtz Center into our Virtual Institute.
 

Recent Publications

All known publications ...
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Final Report
27 pp. () [10.3204/PUBDB-2019-04778]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Pink-beam serial crystallography
Nature Communications 8(1), 1281 () [10.1038/s41467-017-01417-3]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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High-speed fixed-target serial virus crystallography
Nature methods 14, 805-810 () [10.1038/nmeth.4335]  GO  Download fulltext Files  Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Focusing hard x rays beyond the critical angle of total reflection by adiabatically focusing lenses
Applied physics letters 110(10), 101103 () [10.1063/1.4977882]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Characterization of nanowires by coherent x-ray diffractive imaging and ptychography
Hamburg : Verlag Deutsches Elektronen-Synchrotron, DESY-THESIS 149 pp. () [10.3204/PUBDB-2017-01266] = Universität Hamburg, Diss., 2017  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Beamstop-Based Low-Background Ptychography to Image Weakly Scattering Objects
Ultramicroscopy 173, 52 - 57 () [10.1016/j.ultramic.2016.11.005]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Sachbericht 2016 [VH-VI-403]
21 pp. () [10.3204/PUBDB-2019-04875]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dissertation / PhD Thesis  ;
Investigating Cellular Nanoscale with X-Rays : From Proteins to Networks
184 pp. () [10.3204/PUBDB-2016-06090] = University of Göttingen, Diss., 2016  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Use of small-angle X-ray scattering to resolve intracellular structure changes of Escherichia coli cells induced by antibiotic treatment
Journal of applied crystallography 49(6), 2210 - 2216 () [10.1107/S1600576716018562]  GO OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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In Situ Ptychography of Heterogeneous Catalysts using Hard X-Rays: High Resolution Imaging at Ambient Pressure and Elevated Temperature
Microscopy and microanalysis 22(01), 178 - 188 () [10.1017/S1431927615015573]  GO  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2015-02-12, last modified 2015-05-07



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