VH-VI-403
In-Situ Nano-Imaging of Biological and Chemical Processes
Coordinator | Schroer, Christian ; Weckert, Edgar |
Grant period | 2011-2016 |
Funding body | Helmholtz Gemeinschaft Deutscher Forschungszentren |
HGF | |
Identifier | G:(DE-HGF)2015_IFV-VH-VI-403 |
⇧ Impuls- und Vernetzungsfonds ⇧
Note: In the emerging fields of nano science, chemical technology and the life sciences there is an increasing demand for imaging of micro- to nanometer sized objects with highest possible spatial resolution. The physical, chemical, and biological properties of nano-sized objects strongly depend on their structure. Therefore, nanoscopic structure determination is at the heart of understanding biological and chemical processes and is crucial to address the grand challenges in health, environmental, and energy research. X-ray imaging techniques are well suited to these ends, as they provide element specific chemical and structural contrast at high spatial resolution also from the interior of bulk samples or from samples in special environments. The new sources at DESY, PETRA III and FLASH, are ideal to reach these goals. In particular X-ray imaging techniques on the nanoscale directly benefit from the high brilliance of theses sources. In the frame of this Virtual Institute we would like to bring together expertise in x-ray imaging, biology and chemistry to enable in-situ imaging of biological and chemical processes with the xray microscopes at PETRA III and FLASH, and at the European XFEL in the future. In example applications, we will address important questions in biology (membranes, cell ultrastructure, selfassembly mechanisms) and chemistry (catalysis, redox and precipitation reactions), adapting and developing further the x-ray microscopes and special sample environments, such as chemical reactors, microfluidic cells and cryogenic sample environments. Our Virtual Institute comprises groups from four universities (U. Göttingen, U. Heidelberg, KIT Campus South, and TU Dresden) and DESY. The dual affiliation of two scientists to KIT Campus North also brings this Helmholtz Center into our Virtual Institute.All known publications ...
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Report
Final Report
27 pp. (2017) [10.3204/PUBDB-2019-04778]
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Journal Article
Pink-beam serial crystallography
Nature Communications 8(1), 1281 (2017) [10.1038/s41467-017-01417-3]
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Journal Article
High-speed fixed-target serial virus crystallography
Nature methods 14, 805-810 (2017) [10.1038/nmeth.4335]
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Journal Article
Focusing hard x rays beyond the critical angle of total reflection by adiabatically focusing lenses
Applied physics letters 110(10), 101103 (2017) [10.1063/1.4977882]
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Book/Report/Dissertation / PhD Thesis
Characterization of nanowires by coherent x-ray diffractive imaging and ptychography
Hamburg : Verlag Deutsches Elektronen-Synchrotron, DESY-THESIS 149 pp. (2017) [10.3204/PUBDB-2017-01266] = Universität Hamburg, Diss., 2017
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Journal Article
Beamstop-Based Low-Background Ptychography to Image Weakly Scattering Objects
Ultramicroscopy 173, 52 - 57 (2017) [10.1016/j.ultramic.2016.11.005]
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Report
Sachbericht 2016 [VH-VI-403]
21 pp. (2016) [10.3204/PUBDB-2019-04875]
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Dissertation / PhD Thesis
Investigating Cellular Nanoscale with X-Rays : From Proteins to Networks
184 pp. (2016) [10.3204/PUBDB-2016-06090] = University of Göttingen, Diss., 2016
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Use of small-angle X-ray scattering to resolve intracellular structure changes of Escherichia coli cells induced by antibiotic treatment
Journal of applied crystallography 49(6), 2210 - 2216 (2016) [10.1107/S1600576716018562]
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Journal Article
In Situ Ptychography of Heterogeneous Catalysts using Hard X-Rays: High Resolution Imaging at Ambient Pressure and Elevated Temperature
Microscopy and microanalysis 22(01), 178 - 188 (2016) [10.1017/S1431927615015573]
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All known publications ...
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