Journal Article

PUBDB-2025-02070

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Salipro technology in membrane protein research

Mostafavi, S. (Corresponding author)EMBL* ; Fernandes dos Santos Alves Custodio, T.CSSB* ; Jungnickel, K.Extern*CSSB* ; Loew, C. (Corresponding author)CSSB*

2025
Elsevier Amsterdam [u.a.]

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Please use a persistent id in citations: doi:10.1016/j.sbi.2025.103050  doi:10.3204/PUBDB-2025-02070

Abstract: Reconstitution and direct extraction of membrane proteins using saposins is an emerging technique for solubilizing and stabilizing membrane proteins. The Salipro technology offers several advantages over traditional detergent solubilization, including a more native lipid environment, increased protein stability, and maintenance of functionality. This review covers recent studies that have used Salipros to characterize membrane proteins, as well as advances in direct extraction methods that have enabled the structural and functional characterization of a variety of targets.

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Contributing Institute(s):

1. CSSB-EMBL-CL (CSSB-EMBL-CL)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Experiment(s):

1. No specific instrument

Appears in the scientific report 2025

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Database coverage:
; ; ; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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