TY  - JOUR
AU  - Mostafavi, Siavash
AU  - Fernandes dos Santos Alves Custodio, Tania
AU  - Jungnickel, Katharina
AU  - Loew, Christian
TI  - Salipro technology in membrane protein research
JO  - Current opinion in structural biology
VL  - 93
SN  - 0959-440X
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - PUBDB-2025-02070
SP  - 103050 
PY  - 2025
AB  - Reconstitution and direct extraction of membrane proteins using saposins is an emerging technique for solubilizing and stabilizing membrane proteins. The Salipro technology offers several advantages over traditional detergent solubilization, including a more native lipid environment, increased protein stability, and maintenance of functionality. This review covers recent studies that have used Salipros to characterize membrane proteins, as well as advances in direct extraction methods that have enabled the structural and functional characterization of a variety of targets. 
LB  - PUB:(DE-HGF)16
C6  - pmid:40349676
DO  - DOI:10.1016/j.sbi.2025.103050
UR  - https://bib-pubdb1.desy.de/record/631955
ER  -