Journal Article

PUBDB-2026-00227

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Hexagonal and Lamellar Superstructure in DSPE-PEG1000 Monolayers at the Air/Water Interface

Assi, I. ; Ahrens, H.Extern* ; Helm, C. A. (Corresponding author)Extern*

2025
ACS Publ. Washington, DC

This record in other databases:    

Please use a persistent id in citations: doi:10.1021/acs.langmuir.5c03900  doi:10.3204/PUBDB-2026-00227

Abstract: Inspired by diblock copolymer self-assembly, we study lipopolymer monolayers at the air/water interface. We investigated DSPE-PEG1000 (DSPE-EO22) monolayers with alkyl chains in the liquid-condensed phase in dependence of the molecular area. Due to its conformational entropy, the moderately hydrophilic PEG has a larger area requirement than the alkyl chains in all-trans conformation. Small-angle grazing incidence X-ray diffraction (GID) measurements identified a hexagonal superstructure. The ordered alkyl chains form hydrophobic domains that are embedded in dissolved PEG. These domains consist of the alkyl chains of ≈200 PEGylated lipid molecules. During monolayer compression, the number of alkyl chains in a domain remains constant, while their area fraction increases. At an area fraction of 50%, a transition to a lamellar superstructure occurs. During this transition, the alkyl chain domains merge. This transition is attributed to the entropy loss of the laterally compressed PEG chains. Wide-angle GID reveals that the alkyl chains in the liquid-condensed phase possess the same small cross-sectional area (19.75 Å2) as those in DSPE monolayers, indicating that PEG has little influence on the liquid-condensed phase. The hexagonal superstructure was confirmed with AFM images.

---

Contributing Institute(s):

1. DOOR-User (DOOR ; HAS-User)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)
2. SFB 1270 A04 - Elektrisch leitfähige Multischichten für Implantatoberflächen (A04) (384293903) (384293903)

Experiment(s):

1. DORIS Beamline BW1 (DORIS III)

Appears in the scientific report 2025

---

Database coverage:
; ; Clarivate Analytics Master Journal List ; Current Contents - Physical, Chemical and Earth Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---