Journal Article

PUBDB-2025-02031

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Coaxial helium electrospray for single-particle imaging at X-ray free electron lasers

Rafie-Zinedine, S. (Corresponding author)XFEL.EU* ; Schulz, J. ; Bielecki, J. ; Heymann, M. (Corresponding author)Extern*XFEL.EU*

2025
IUCr Chester

This record in other databases:      

Please use a persistent id in citations: doi:10.1107/S1600577525003686  doi:10.3204/PUBDB-2025-02031

Abstract: Single-particle imaging at X-ray free-electron lasers relies on suitable sample injection of nanoscale macromolecules and particles into the gas phase at room temperature. A coaxial liquid-sheet strategy considerably extended the range of suitable samples to include conductivities from zero to 40000 µS cm$^{−1}$ – a more than about an eightfold increase in range compared with conventional electrosprays. A helium chamber atmosphere in combination with an engineered gas-sheet protected aerosol formation against corona discharge and reduced background noise more than threefold. These results suggest new avenues to qualify ever more demanding biological and material science samples for single-particle imaging in the future.

---

Contributing Institute(s):

1. Sample Environment and Characterisation (XFEL_E2_SEC)

Research Program(s):

1. 6G13 - Accelerator of European XFEL (POF4-6G13) (POF4-6G13)

Experiment(s):

1. Experiments at XFEL

Appears in the scientific report 2025

---

Database coverage:
; ; ; ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Physical, Chemical and Earth Sciences ; DEAL Wiley ; DOAJ Seal ; Ebsco Academic Search ; Essential Science Indicators ; Fees ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---