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@ARTICLE{RafieZinedine:631519,
author = {Rafie-Zinedine, Safi and Schulz, Joachim and Bielecki,
Johan and Heymann, Michael},
title = {{C}oaxial helium electrospray for single-particle imaging
at {X}-ray free electron lasers},
journal = {Journal of synchrotron radiation},
volume = {32},
number = {4},
issn = {0909-0495},
address = {Chester},
publisher = {IUCr},
reportid = {PUBDB-2025-02031},
pages = {849 - 860},
year = {2025},
abstract = {Single-particle imaging at X-ray free-electron lasers
relies on suitable sample injection of nanoscale
macromolecules and particles into the gas phase at room
temperature. A coaxial liquid-sheet strategy considerably
extended the range of suitable samples to include
conductivities from zero to 40000 µS cm$^{−1}$ – a
more than about an eightfold increase in range compared with
conventional electrosprays. A helium chamber atmosphere in
combination with an engineered gas-sheet protected aerosol
formation against corona discharge and reduced background
noise more than threefold. These results suggest new avenues
to qualify ever more demanding biological and material
science samples for single-particle imaging in the future.},
cin = {$XFEL_E2_SEC$},
ddc = {550},
cid = {$I:(DE-H253)XFEL_E2_SEC-20210408$},
pnm = {6G13 - Accelerator of European XFEL (POF4-6G13)},
pid = {G:(DE-HGF)POF4-6G13},
experiment = {EXP:(DE-H253)XFEL-Exp-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40478665},
doi = {10.1107/S1600577525003686},
url = {https://bib-pubdb1.desy.de/record/631519},
}