Journal Article PUBDB-2024-06199

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Numerical analysis of Knudsen number of helium flow through gas-focused liquid sheet micro-nozzle

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2024
MDPI Belgrade

Fluids 9(12), 273 () [10.3390/fluids9120273]
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Abstract: This work aims to verify whether the continuum mechanics assumption holds for the numerical simulation of a typical sample delivery system in Serial Femtosecond Crystallography (SFX). Knudsen numbers were calculated based on the numerical simulation results of helium flow through the gas-focused liquid sheet nozzle into the vacuum chamber, representing the upper limit of Knudsen number for such systems. The analysed flow is considered steady, compressible and laminar. The numerical results are mesh-independent, with a Grid Convergence Index signifi-cantly lower than 1 % for global and local analysis. The study is based on an improved definition of the numerical Knudsen number, a combination of cell Knudsen number and physical Knudsen number. In the analysis, no-slip boundary and low-pressure boundary slip conditions are com-pared. No significant differences are observed. The study justifies using computational fluid dy-namics (CFD) analysis for SFX sample delivery systems based on the assumption of continuum mechanics.

Classification:

Contributing Institute(s):
  1. FS-Arbeitsgruppe (FS-ML)
Research Program(s):
  1. 633 - Life Sciences – Building Blocks of Life: Structure and Function (POF4-633) (POF4-633)
  2. DFG project G:(GEPRIS)390715994 - EXC 2056: CUI: Advanced Imaging of Matter (390715994) (390715994)
  3. DFG project G:(GEPRIS)194651731 - EXC 1074: Hamburger Zentrum für ultraschnelle Beobachtung (CUI): Struktur, Dynamik und Kontrolle von Materie auf atomarer Skala (194651731) (194651731)
Experiment(s):
  1. No specific instrument

Appears in the scientific report 2024
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Medline ; Creative Commons Attribution CC BY 4.0 ; DOAJ ; OpenAccess ; Article Processing Charges ; Clarivate Analytics Master Journal List ; DOAJ Seal ; Emerging Sources Citation Index ; Fees ; SCOPUS ; Web of Science Core Collection
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 Record created 2024-10-08, last modified 2025-07-15