Journal Article

PUBDB-2024-05738

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png A concise guide to choosing suitable gene expression systems for recombinant protein production

Schütz, A. ; Bernhard, F. ; Berrow, N. ; Buyel, J. F. ; Ferreira-da-Silva, F. ; Haustraete, J. ; van den Heuvel, J. ; Hoffmann, J.-E. ; de Marco, A. ; Peleg, Y. ; Suppmann, S. ; Unger, T. ; Vanhoucke, M. ; Witt, S.CSSB* ; Remans, K. (Corresponding author)

2023
Elsevier Amsterdam

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Please use a persistent id in citations: doi:10.1016/j.xpro.2023.102572  doi:10.3204/PUBDB-2024-05738

Abstract: This overview guides both novices and experienced researchers facing challenging targets to select the most appropriate gene expression system for producing a particular protein. By answering four key questions, readers can determine the most suitable gene expression system following a decision scheme. This guide addresses the most commonly used and accessible systems and provides brief descriptions of the main gene expression systems’ key characteristics to assist decision making. Additionally, information has been included for selected less frequently used “exotic” gene expression systems.

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Contributing Institute(s):

1. CSSB - Core Facility - Protein Production (CSSB-CF-PP)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Experiment(s):

1. No specific instrument

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Database coverage:
; ; ; ; Article Processing Charges ; DOAJ Seal ; Fees ; PubMed Central ; SCOPUS

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