Journal Article PUBDB-2023-06361

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FLASHlab@PITZ: New R&D platform with unique capabilities for electron FLASH and VHEE radiation therapy and radiation biology under preparation at PITZ

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2023
Elsevier Amsterdam

Physica medica 104, 174 - 187 () [10.1016/j.ejmp.2022.10.026]
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Abstract: At the Photo Injector Test facility at DESY in Zeuthen (PITZ), an R&D platform for electron FLASH and very highenergy electron radiation therapy and radiation biology is being prepared (FLASHlab@PITZ). The beam parametersavailable at PITZ are worldwide unique. They are based on experiences from 20 + years of developinghigh brightness beam sources and an ultra-intensive THz light source demonstrator for ps scale electron buncheswith up to 5 nC bunch charge at MHz repetition rate in bunch trains of up to 1 ms length, currently 22 MeV(upgrade to 250 MeV planned). Individual bunches can provide peak dose rates up to 1014 Gy/s, and 10 Gy canbe delivered within picoseconds. Upon demand, each bunch of the bunch train can be guided to a differenttransverse location, so that either a “painting” with micro beams (comparable to pencil beam scanning in protontherapy) or a cumulative increase of absorbed dose, using a wide beam distribution, can be realized at the tumor.Full tumor treatment can hence be completed within 1 ms, mitigating organ movement issues. With extremelyflexible beam manipulation capabilities, FLASHlab@PITZ will cover the current parameter range of successfully

Classification:

Contributing Institute(s):
  1. Technologie (Z_PITZ)
  2. Z_DET (Z_DET)
  3. beautragt von UNI/EXP (CFEL-NOVA)
Research Program(s):
  1. 621 - Accelerator Research and Development (POF4-621) (POF4-621)
Experiment(s):
  1. Photo Injector Test Facility

Appears in the scientific report 2023
Database coverage:
Medline ; Embargoed OpenAccess ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Essential Science Indicators ; IF < 5 ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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Private Collections > >CFEL > >UNI-CFEL > CFEL-NOVA
Private Collections > >DESY > >ZEUTHEN > Z_PITZ
Private Collections > >DESY > >ZEUTHEN > Z_DET
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 Record created 2023-10-23, last modified 2026-04-27


Published on 2022-12-01. Available in OpenAccess from 2023-12-01.:
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