Contribution to a book PUBDB-2019-00073

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Structure Determination by Continuous Diffraction from Imperfect Crystals

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2018
Springer Nature Cham
ISBN: 978-3-030-00550-4, 9783030005504 (print), 9783030005528 (print)

[Ebook] X-ray Free Electron Lasers : A Revolution in Structural Biology / Boutet, Sébastien ; Fromme, Petra ; Hunter, Mark S. , Cham : Springer International Publishing, 2018, Cham : Springer Nature 253-300 () [10.1007/978-3-030-00551-1_9]  GO

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Abstract: The coherent diffraction pattern of a non-periodic finite object does not consist of Bragg peaks but is continuously and smoothly varying. Such patterns do not suffer from the well-known phase problem of crystallography. In this case, robust iterative algorithms exist to determine the electron density of the object from the diffraction pattern alone. Continuous diffraction is accessible from ensembles of aligned molecules, including disordered protein crystals. We discuss the application of the concepts of coherent diffractive imaging to such cases and describe the experimental considerations to adequately measure the weak continuous diffraction signals.

Classification:

Note: © Springer Nature Switzerland AG

Contributing Institute(s):
  1. FS-CFEL-1 (Group Leader: Henry Chapman) (CFEL-I)
  2. CFEL-Coherent X-Ray Imaging (FS-CFEL-1)
Research Program(s):
  1. 6215 - Soft Matter, Health and Life Sciences (POF3-621) (POF3-621)
  2. Leibniz Preis - Leibiz Programm 2015: Prof. Dr. Henry N. Chapman (DFG-Leibniz-2015-Chapman) (DFG-Leibniz-2015-Chapman)
  3. AXSIS - Frontiers in Attosecond X-ray Science: Imaging and Spectroscopy (609920) (609920)
Experiment(s):
  1. Experiments at CFEL
  2. Measurement at external facility

Appears in the scientific report 2018
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 Record created 2019-01-07, last modified 2025-07-29


Published on 2018-12-28. Available in OpenAccess from 2020-12-28.:
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