Journal Article

PUBDB-2017-02113

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Vesicle Origami: Cuboid Phospholipid Vesicles Formed by Template-Free Self-Assembly

Neuhaus, F.Extern* ; Mueller, D. ; Tanasescu, R.Extern* ; Balog, S. ; Ishikawa, T. ; Brezesinski, G.Extern* ; Zumbuehl, A. (Corresponding author)Extern*

2017
Wiley Weinheim

This record in other databases:        

Please use a persistent id in citations: doi:10.1002/anie.201701634  doi:10.3204/PUBDB-2017-02113

Abstract: Phospholipid liposomes are archetypical self-assembled structures. To minimize the surface tension, the vesicles typically are spherical. Deciphering the bilayer code, the basic physical interactions between phospholipids would allow these molecules to be utilized as building blocks for novel, non-spherical structures. A 1,2-diamidophospholipid is presented that self-assembles into a cuboid structure. Owing to intermolecular hydrogen bonding, the bilayer membranes form an exceptionally tight subgel packing, leading to a maximization of flat structural elements and a minimization of any edges. These conditions are optimized in the geometrical structure of a cube. Surprisingly, the lateral surface pressure in the membrane is only one third of the value typically assumed for a bilayer membrane, questioning a long-standing rule-of-thumb.

Note: ©Wiley-VCH Verlag GmbH & Co.KgaA, Weinheim

---

Contributing Institute(s):

1. DOOR-User (DOOR)

Research Program(s):

1. 6G3 - PETRA III (POF3-622) (POF3-622)
2. FS-Proposal: I-20150282 EC (I-20150282-EC) (I-20150282-EC)

Experiment(s):

1. PETRA Beamline P08 (PETRA III)

Appears in the scientific report 2017

---

Database coverage:
; ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; IF >= 10 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

---