Journal Article

PUBDB-2025-00050

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Present and future structural biology activities at DESY and the European XFEL

Oberthür, D.CFEL*XFEL.EU*DESY* ; Hakanpää, J.DESY* ; Chatziefthymiou, S.Extern*DESY* ; Pompidor, G.DESY* ; Bean, R. ; Chapman, H. N.CFEL*XFEL.EU*DESY* ; Weckert, E. (Corresponding author)DESY*

2025
IUCr Chester

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Please use a persistent id in citations: doi:10.1107/S1600577525000669  doi:10.3204/PUBDB-2025-00050

Abstract: Structural biology investigations using synchrotron radiation have a long history at the photon science facilities at DESY. Presently, EMBL and DESY operate state-of-the-art macromolecular crystallography and biological SAXS stations at the synchrotron radiation source PETRA III for the international user community. New experimental opportunities for experiments with femtosecond temporal resolution and for extremely small macromolecular crystals have become available with the advent of X-ray free-electron lasers (XFELs) such as the European XFEL. Within large international collaborations, groups at DESY and the European XFEL have contributed significantly to the development of experimental and data analysis methods to enable serial crystallography experiments at both XFELs and high-brilliance synchrotron radiation sources. The available portfolio of analytical infrastructure in photon science at DESY has attracted several campus partners to contribute to the development of instruments and methods and provide their own complementary experimental techniques, thereby establishing a fruitful scientific environment to make significant contributions to present and future societal challenges in the field of life sciences.

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Contributing Institute(s):

1. FS-CFEL-1 (Group Leader: Henry Chapman) (CFEL-I)

Research Program(s):

1. 633 - Life Sciences – Building Blocks of Life: Structure and Function (POF4-633) (POF4-633)
2. 6G3 - PETRA III (DESY) (POF4-6G3) (POF4-6G3)

Experiment(s):

1. PETRA Beamline P11 (PETRA III)

Appears in the scientific report 2025

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