Journal Article

PUBDB-2024-08060

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Enhanced Organocatalytic Processes through an Engineered Acid‐Base Site Bifunctional Pore in a Zirconium Metal‐Organic Framework

Moreno, J. M. ; Gil-San-Millan, R. ; Mas-Ballesté, R. ; Alemán, J. (Corresponding author) ; Platero-Prats, A. E. (Corresponding author)Extern*

2024
Wiley-VCH Weinheim

This record in other databases:      

Please use a persistent id in citations: doi:10.1002/cctc.202400676  doi:10.3204/PUBDB-2024-08060

Abstract: This work introduces a robust acid-base catalytic system based on the zirconium-based metal-organic framework (Zr-MOF) MOF-808, selected for its open structure, high stability, and low presence of structural defects compared to other Zr-MOFs. Four bifunctional benzoate ligands bearing free carboxylic acid (-COOH) and nitrogen-containing groups were introduced into the MOF-808 using solvent-assisted ligand exchange methods. Unlike other materials, the acid and base sites in the bifunctional MOF-808 materials are situated in the same capping ligand, leading to a bifunctional behavior between the two neighboring sites. The system was tested for Knoevenagel condensation and deacetylation-Knoevenagel tandem reactions, demonstrating high catalytic activity and excellent yields. Additionally, computational modeling provided insights into the catalytic mechanism and the role of the acid-base sites. The study provides a better understanding of the unique behavior of the bifunctional MOF-808 catalyst and offers prospects for designing new and efficient catalytic systems for organocatalysis.

---

Contributing Institute(s):

1. DOOR-User (DOOR ; HAS-User)

Research Program(s):

1. 6G3 - PETRA III (DESY) (POF4-6G3) (POF4-6G3)
2. FS-Proposal: I-20211230 EC (I-20211230-EC) (I-20211230-EC)

Experiment(s):

1. PETRA Beamline P02.1 (PETRA III)

Appears in the scientific report 2024

---

Database coverage:
; ; ; Clarivate Analytics Master Journal List ; Current Contents - Physical, Chemical and Earth Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---