Journal Article

PHPPUBDB-24926

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Solution structure of natively assembled yeast ribosomal stalk determined by Small Angle X-ray Scattering

Grela, P. ; Gajda, M. J. ; Armache, J. P. ; Beckmann, R. ; Krokowski, D. ; Svergun, D. I. ; Grankowski, N. ; Tchorzewski, M. (Corresponding author) ; DESY

2012
Portland Press London

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Please use a persistent id in citations: doi:10.1042/BJ20120115

Abstract: The ribosomal stalk of the 60S subunit has been shown to play a crucial role in all steps of protein synthesis, but its structure and exact molecular function remain an unanswered question. In the present study, we show the low-resolution models of the solution structure of the yeast ribosomal stalk, composed of five proteins, P0-(P1-P2)(2). The model of the pentameric stalk complex determined by small-angle X-ray scattering reveals an elongated shape with a maximum length of 13 nm. The model displays three distinct lobes, which may correspond to the individual P1-P2 heterodimers anchored to the C-terminal domain of the P0 protein.

Keyword(s): Protein Binding: physiology (MeSH) ; Protein Multimerization (MeSH) ; Protein Structure, Tertiary (MeSH) ; Ribosomal Proteins: chemistry (MeSH) ; Saccharomyces cerevisiae: chemistry (MeSH) ; Saccharomyces cerevisiae Proteins: chemistry (MeSH) ; Scattering, Small Angle (MeSH) ; X-Ray Diffraction: methods (MeSH) ; RPP0 protein, S cerevisiae ; Ribosomal Proteins ; Saccharomyces cerevisiae Proteins ; ribosomal protein P0

Note: ISSN 1470-8728 not unique: **2 hits**.

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Contributing Institute(s):

1. EMBL (EMBL(-2012))

Research Program(s):

1. DORIS Beamline D1.2 (POF2-54G13) (POF2-54G13)

Experiment(s):

1. DORIS Beamline D1.2 (DORIS III)

Appears in the scientific report 2012

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Database coverage:
; ; Allianz-Lizenz / DFG ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; JCR ; No Author Disambiguation ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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