Processing of XFEL Data

Wlodawer, Alexander; White, Thomas A.; Jaskolski, Mariusz; Dauter, Zbigniew

doi:10.1007/978-1-4939-7000-1_13

Contribution to a book

PUBDB-2017-11815

Processing of XFEL Data

Wlodawer, A. (Editor) ; Dauter, Z. (Editor) ; Jaskolski, M. (Editor) ; White, T. A. (Corresponding author)CFEL*DESY*

2017
Springer New York New York, NY
ISBN: 978-1-4939-6998-2 (print), 978-1-4939-7000-1 (electronic)

Protein Crystallography / Wlodawer, Alexander (Editor) ; New York, NY : Springer New York, 2017, Chapter 13 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-6998-2=978-1-4939-7000-1 ; doi:10.1007/978-1-4939-7000-1 New York, NY : Springer New York, Methods in Molecular Biology 1607, 325-347 (2017) [10.1007/978-1-4939-7000-1_13]

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Abstract: The introduction of the X-ray laser to crystallography, and its impact on the types of crystallographic experiments being performed as described in the previous chapter, has meant that new data processing strategies had to be found. While some XFEL crystallography experiments approach the conventional methods quite closely, even those are not without special considerations relating to data processing. Serial femtosecond crystallography (SFX) introduces several additional problems, many of which have been solved recently, and there has been great progress towards resolving the remaining ones. Recent developments into the use of continuous scattering between the Bragg peaks will need even greater changes to the conventional data processing methods. This chapter describes the special characteristics of XFEL data and introduces the range of processing methods which are currently under development.

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