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2022-09-26
16:56

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2022-09-26
16:42
DBCoverage [PUBDB-2022-04923] Journal Article
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NMR-derived secondary structure of the full-length Ox40 mRNA 3′UTR and its multivalent binding to the immunoregulatory RBP Roquin
Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and differentiation. mRNA lifetime is governed by cis-regulatory elements in their 3′ untranslated regions (UTR). [...]
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2022-09-26
16:19
DBCoverage [PUBDB-2022-04922] Journal Article
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A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host
The Kaposi’s sarcoma associated herpesvirus protein ORF45 binds the extracellular signal-regulated kinase (ERK) and the p90 Ribosomal S6 kinase (RSK). ORF45 was shown to be a kinase activator in cells but a kinase inhibitor in vitro, and its effects on the ERK-RSK complex are unknown. [...]
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2022-09-26
10:58
arXiv [PUBDB-2022-04914] Contribution to a conference proceedings/Journal Article
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High-energy and ultra-high-energy neutrinos: A Snowmass white paper
[arXiv:2203.08096]
2022 Snowmass Summer Study, SeattleSeattle, United States, 17 Jul 2022 - 26 Jul 20222022-07-172022-07-26 Journal of high energy astrophysics 36, 55 - 110 () [10.1016/j.jheap.2022.08.001]  GO
Astrophysical neutrinos are excellent probes of astroparticle physics and high-energy physics. With energies far beyond solar, supernovae, atmospheric, and accelerator neutrinos, high-energy and ultra-high-energy neutrinos probe fundamental physics from the TeV scale to the EeV scale and beyond. [...]

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2022-09-23
17:37
DBCoverage [PUBDB-2022-04911] Journal Article
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Gadolinium and Bio-Metal Association: A Concentration Dependency Tested in a Renal Allograft and Investigated by Micro-Synchrotron XRF
Aims: This study aimed to investigate gadolinium (Gd) and bio-metals in a renal allograft of a patient who was shortly after transplantation repeatedly exposed to a Gd-based contrast agent (GBCA), with the purpose of determining whether Gd can be proven and spatially and quantitatively imaged. Further elemental associations between Gd and bio-metals were also investigated. [...]
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2022-09-23
15:46
DBCoverage [PUBDB-2022-04910] Journal Article
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Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding
IUCrJ 9(5), 666 - 681 () [10.1107/S2052252522007175]  GO
The recently discovered lytic polysaccharide monooxygenases (LPMOs) are Cu-containing enzymes capable of degrading polysaccharide substrates oxidatively. The generally accepted first step in the LPMO reaction is the reduction of the active-site metal ion from Cu2+ to Cu+. [...]
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2022-09-23
14:25
DBCoverage [PUBDB-2022-04897] Journal Article
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Wire and arc additive manufacturing of 316L stainless steel/Inconel 625 functionally graded material: development and characterization
In this work, a 316L stainless steel to Inconel 625 functionally graded material (FGM) wasbuilt using different deposition strategies (named as direct and smooth-type interfaces) byTwin-Wire and Arc Additive Manufacturing (T-WAAM). This combination of materials is ofinterest in chemical plants, oil & gas, and nuclear applications, where high corrosion andwear resistance are essential requirements. [...]
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2022-09-23
10:41
arXiv [PUBDB-2022-04881] Journal Article
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Search for Dark Matter Annihilation Signals in the H.E.S.S. Inner Galaxy Survey
[arXiv:2207.10471]
The central region of the Milky Way is one of the foremost locations to look for dark matter (DM) signatures. We report the first results on a search for DM particle annihilation signals using new observations from an unprecedented γ-ray survey of the Galactic Center (GC) region, i.e., the Inner Galaxy Survey, at very high energies (≳100 GeV) performed with the H.E.S.S. [...]
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2022-09-23
10:38

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2022-09-23
10:31
DBCoverage [PUBDB-2022-04879] Journal Article
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The fifth-order post-Newtonian Hamiltonian dynamics of two-body systems from an effective field theory approach
[DESY 21--151; DESY-21-151; DO--TH 21/27; SAGEX--21--30; arXiv:2110.13822]
Within an effective field theory method to general relativity, we calculate the fifth-order post–Newtonian (5PN) Hamiltonian dynamics also for the tail terms, extending earlier work on the potential contributions, working in harmonic coordinates. Here we calculate independently all (local) 5PN far-zone contributions using the in–in formalism, on which we give a detailed account. [...]
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