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@INPROCEEDINGS{Tarakci:643493,
author = {Tarakci, Elif},
title = {{NORMAL} {TISSUE} {SPARING} {WITH} {ELECTRON} {BEAMS} {AT}
{PITZ}: {FIRST} {IRRADIATION} {STUDY} {IN} {ZEBRAFISH}
{EMBRYOS}},
school = {DESY},
reportid = {PUBDB-2026-00240},
year = {2025},
abstract = {FLASH irradiation has emerged as a promising approach to
reduce normal tissue toxicity while preserving tumor
control, creating a need for sensitive models to study its
biological effects. Zebrafish (Danio rerio) embryos provide
such a model, offering a vertebrate system with high
developmental sensitivity, genetic similarity to humans, and
suitability for preclinical radiation biology research.
Within the $R\&D$ platform FLASHlab@PITZ, a collaboration
between the Photo Injector Test Facility at DESY in Zeuthen
(PITZ), the Technical University of Applied Sciences Wildau,
Charité – Universitätsmedizin Berlin, and the
Max-Delbrück Center (MDC), we aim to establish zebrafish as
a robust in vivo system to characterize radiation-induced
toxicities. In this study, we evaluated the effects of
conventional X-rays, electron low dose rate (LDR), and
electron high dose rate (HDR, FLASH-like) irradiation on
wild-type AB zebrafish embryos at 24 hours
post-fertilization (hpf).},
month = {Dec},
date = {2025-12-10},
organization = {frpt 2025, prague (Czech Republic), 10
Dec 2025 - 12 Dec 2025},
cin = {$Z_PITZ$},
cid = {$I:(DE-H253)Z_PITZ-20210408$},
pnm = {621 - Accelerator Research and Development (POF4-621)},
pid = {G:(DE-HGF)POF4-621},
experiment = {EXP:(DE-H253)PITZ-20150101},
typ = {PUB:(DE-HGF)24},
url = {https://bib-pubdb1.desy.de/record/643493},
}