TY  - CONF
AU  - Tarakci, Elif
TI  - NORMAL TISSUE SPARING WITH ELECTRON BEAMS AT PITZ: FIRST IRRADIATION STUDY IN ZEBRAFISH EMBRYOS
PB  - DESY
M1  - PUBDB-2026-00240
PY  - 2025
AB  - FLASH irradiation has emerged as a promising approach to reduce normal tissue toxicity while preserving tumor control, creating a need for sensitive models to study its biological effects. Zebrafish (Danio rerio) embryos provide such a model, offering a vertebrate system with high developmental sensitivity, genetic similarity to humans, and suitability for preclinical radiation biology research. Within the R</td><td width="150">
AB  - D platform FLASHlab@PITZ, a collaboration between the Photo Injector Test Facility at DESY in Zeuthen (PITZ), the Technical University of Applied Sciences Wildau, Charité – Universitätsmedizin Berlin, and the Max-Delbrück Center (MDC), we aim to establish zebrafish as a robust in vivo system to characterize radiation-induced toxicities. In this study, we evaluated the effects of conventional X-rays, electron low dose rate (LDR), and electron high dose rate (HDR, FLASH-like) irradiation on wild-type AB zebrafish embryos at 24 hours post-fertilization (hpf).
T2  - frpt 2025
CY  - 10 Dec 2025 - 12 Dec 2025, prague (Czech Republic)
Y2  - 10 Dec 2025 - 12 Dec 2025
M2  - prague, Czech Republic
LB  - PUB:(DE-HGF)24
UR  - https://bib-pubdb1.desy.de/record/643493
ER  -