000643493 001__ 643493
000643493 005__ 20260114103304.0
000643493 037__ $$aPUBDB-2026-00240
000643493 041__ $$aEnglish
000643493 1001_ $$0P:(DE-H253)PIP1108811$$aTarakci, Elif$$b0$$eCorresponding author
000643493 1112_ $$afrpt 2025$$cprague$$d2025-12-10 - 2025-12-12$$wCzech Republic
000643493 245__ $$aNORMAL TISSUE SPARING WITH ELECTRON BEAMS AT PITZ: FIRST IRRADIATION STUDY IN ZEBRAFISH EMBRYOS
000643493 260__ $$c2025
000643493 3367_ $$033$$2EndNote$$aConference Paper
000643493 3367_ $$2BibTeX$$aINPROCEEDINGS
000643493 3367_ $$2DRIVER$$aconferenceObject
000643493 3367_ $$2ORCID$$aCONFERENCE_POSTER
000643493 3367_ $$2DataCite$$aOutput Types/Conference Poster
000643493 3367_ $$0PUB:(DE-HGF)24$$2PUB:(DE-HGF)$$aPoster$$bposter$$mposter$$s1768383122_3311986
000643493 502__ $$cDESY
000643493 520__ $$aFLASH irradiation has emerged as a promising approach to reduce normal tissue toxicity while preserving tumor control, creating a need for sensitive models to study its biological effects. Zebrafish (Danio rerio) embryos provide such a model, offering a vertebrate system with high developmental sensitivity, genetic similarity to humans, and suitability for preclinical radiation biology research. Within the R&D platform FLASHlab@PITZ, a collaboration between the Photo Injector Test Facility at DESY in Zeuthen (PITZ), the Technical University of Applied Sciences Wildau, Charité – Universitätsmedizin Berlin, and the Max-Delbrück Center (MDC), we aim to establish zebrafish as a robust in vivo system to characterize radiation-induced toxicities. In this study, we evaluated the effects of conventional X-rays, electron low dose rate (LDR), and electron high dose rate (HDR, FLASH-like) irradiation on wild-type AB zebrafish embryos at 24 hours post-fertilization (hpf).
000643493 536__ $$0G:(DE-HGF)POF4-621$$a621 - Accelerator Research and Development (POF4-621)$$cPOF4-621$$fPOF IV$$x0
000643493 693__ $$0EXP:(DE-H253)PITZ-20150101$$5EXP:(DE-H253)PITZ-20150101$$ePhoto Injector Test Facility$$x0
000643493 8564_ $$uhttps://bib-pubdb1.desy.de/record/643493/files/FRPT_Tarakci_abstract.pdf$$yRestricted
000643493 8564_ $$uhttps://bib-pubdb1.desy.de/record/643493/files/FRPT_Tarakci_poster.pdf$$yRestricted
000643493 8564_ $$uhttps://bib-pubdb1.desy.de/record/643493/files/FRPT_Tarakci_abstract.pdf?subformat=pdfa$$xpdfa$$yRestricted
000643493 8564_ $$uhttps://bib-pubdb1.desy.de/record/643493/files/FRPT_Tarakci_poster.pdf?subformat=pdfa$$xpdfa$$yRestricted
000643493 9101_ $$0I:(DE-588b)2008985-5$$6P:(DE-H253)PIP1108811$$aDeutsches Elektronen-Synchrotron$$b0$$kDESY
000643493 9131_ $$0G:(DE-HGF)POF4-621$$1G:(DE-HGF)POF4-620$$2G:(DE-HGF)POF4-600$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bForschungsbereich Materie$$lMaterie und Technologie$$vAccelerator Research and Development$$x0
000643493 9201_ $$0I:(DE-H253)Z_PITZ-20210408$$kZ_PITZ$$lTechnologie$$x0
000643493 980__ $$aposter
000643493 980__ $$aEDITORS
000643493 980__ $$aVDBINPRINT
000643493 980__ $$aI:(DE-H253)Z_PITZ-20210408
000643493 980__ $$aUNRESTRICTED