%0 Conference Paper
%A Tarakci, Elif
%T NORMAL TISSUE SPARING WITH ELECTRON BEAMS AT PITZ: FIRST IRRADIATION STUDY IN ZEBRAFISH EMBRYOS
%I DESY
%M PUBDB-2026-00240
%D 2025
%X FLASH irradiation has emerged as a promising approach to reduce normal tissue toxicity while preserving tumor control, creating a need for sensitive models to study its biological effects. Zebrafish (Danio rerio) embryos provide such a model, offering a vertebrate system with high developmental sensitivity, genetic similarity to humans, and suitability for preclinical radiation biology research. Within the R</td><td width="150">
%X D platform FLASHlab@PITZ, a collaboration between the Photo Injector Test Facility at DESY in Zeuthen (PITZ), the Technical University of Applied Sciences Wildau, Charité – Universitätsmedizin Berlin, and the Max-Delbrück Center (MDC), we aim to establish zebrafish as a robust in vivo system to characterize radiation-induced toxicities. In this study, we evaluated the effects of conventional X-rays, electron low dose rate (LDR), and electron high dose rate (HDR, FLASH-like) irradiation on wild-type AB zebrafish embryos at 24 hours post-fertilization (hpf).
%B frpt 2025
%C 10 Dec 2025 - 12 Dec 2025, prague (Czech Republic)
Y2 10 Dec 2025 - 12 Dec 2025
M2 prague, Czech Republic
%F PUB:(DE-HGF)24
%9 Poster
%U https://bib-pubdb1.desy.de/record/643493