TY  - JOUR
AU  - Anthuparambil, Nimmi Das
AU  - Kowalski, Marvin
AU  - Timmermann, Sonja
AU  - Westermeier, Fabian
AU  - Weschke, Daniel
AU  - Ziolkowski, Michael
AU  - Heidbrink, Stefan
AU  - Dargasz, Michelle
AU  - Paulus, Michael
AU  - Sprung, Michael
AU  - Gutt, Christian
TI  - A 250 Hz fast shutter with flexible sampling schemes for low-dose XPCS experiments at beamline P10 at PETRA III
JO  - Journal of physics / Conference Series
VL  - 3010
IS  - 1
SN  - 1742-6588
CY  - Bristol
PB  - IOP Publ.
M1  - PUBDB-2025-02614
SP  - 012095 
PY  - 2025
AB  - Low-dose X-ray photon correlation spectroscopy experiments on biological samples can be used to investigate the structure formation and underlying dynamics during phase separation, denaturation, and gelation. However, the use of intensive X-ray beams as an investigative tool is limited due to the susceptibility of biological samples to radiation-induced changes. XPCS in particular requires recording a series of high-frame-rate images to capture fast dynamics. In such cases, a fast X-ray shutter system is required to minimize beam damage to the samples by allowing a flexible delay between two images. Here we show how a fast (250 Hz) X-ray shutter system, built by the University of Siegen in close collaboration with DESY, improves low-dose XPCS capabilities at the P10 beamline at PETRA III. We found that by employing this shutter system in a logarithmic sampling scheme, the absorbed X-ray dose on the samples could be significantly decreased. 
LB  - PUB:(DE-HGF)16
DO  - DOI:10.1088/1742-6596/3010/1/012095
UR  - https://bib-pubdb1.desy.de/record/634790
ER  -