%0 Journal Article
%A Anthuparambil, Nimmi Das
%A Kowalski, Marvin
%A Timmermann, Sonja
%A Westermeier, Fabian
%A Weschke, Daniel
%A Ziolkowski, Michael
%A Heidbrink, Stefan
%A Dargasz, Michelle
%A Paulus, Michael
%A Sprung, Michael
%A Gutt, Christian
%T A 250 Hz fast shutter with flexible sampling schemes for low-dose XPCS experiments at beamline P10 at PETRA III
%J Journal of physics / Conference Series
%V 3010
%N 1
%@ 1742-6588
%C Bristol
%I IOP Publ.
%M PUBDB-2025-02614
%P 012095 
%D 2025
%X Low-dose X-ray photon correlation spectroscopy experiments on biological samples can be used to investigate the structure formation and underlying dynamics during phase separation, denaturation, and gelation. However, the use of intensive X-ray beams as an investigative tool is limited due to the susceptibility of biological samples to radiation-induced changes. XPCS in particular requires recording a series of high-frame-rate images to capture fast dynamics. In such cases, a fast X-ray shutter system is required to minimize beam damage to the samples by allowing a flexible delay between two images. Here we show how a fast (250 Hz) X-ray shutter system, built by the University of Siegen in close collaboration with DESY, improves low-dose XPCS capabilities at the P10 beamline at PETRA III. We found that by employing this shutter system in a logarithmic sampling scheme, the absorbed X-ray dose on the samples could be significantly decreased. 
%F PUB:(DE-HGF)16
%9 Journal Article
%R 10.1088/1742-6596/3010/1/012095
%U https://bib-pubdb1.desy.de/record/634790