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000631954 1001_ $$0P:(DE-H253)PIP1094699$$aGabriel, Florian$$b0
000631954 245__ $$aMembrantransport von Thiamin im menschlichen Körper
000631954 260__ $$aHeidelberg$$bSpringer Nature$$c2025
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000631954 520__ $$aThiamine (vitamin B$_1$) is an essential coenzyme for central metabolic pathways. Metazoans, including humans, have to take up thiamine via the solute carriers SLC19A2 and SLC19A3, because they lost the ability to synthesize thiamine de novo. Perturbation of these transport systems has severe effects on human health. Here we discuss the molecular mechanisms of thiamine recognition, transport and inhibition based on recently available cryo-Electron Microscopy structures of SLC19A3.
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000631954 7001_ $$0P:(DE-H253)PIP1023783$$aLoew, Christian$$b1$$eCorresponding author
000631954 773__ $$0PERI:(DE-600)2203536-9$$a10.1007/s12268-025-2462-4$$gVol. 31, no. 3, p. 266 - 268$$n3$$p266 - 268$$tBiospektrum$$v31$$x0947-0867$$y2025
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