TY  - JOUR
AU  - Ahmed, Abdullah A. A.
AU  - Alegret, Nuria
AU  - Almeida, Bethany
AU  - Alvarez-Puebla, Ramón
AU  - Andrews, Anne M.
AU  - Ballerini, Laura
AU  - Barrios-Capuchino, Juan J.
AU  - Becker, Charline
AU  - Blick, Robert H.
AU  - Bonakdar, Shahin
AU  - Chakraborty, Indranath
AU  - Chen, Xiaodong
AU  - Cheon, Jinwoo
AU  - Chilla, Gerwin
AU  - Coelho Conceicao, Andre Luiz
AU  - Delehanty, James
AU  - Dulle, Martin
AU  - Efros, Alexander L.
AU  - Epple, Matthias
AU  - Fedyk, Mark
AU  - Feliu, Neus
AU  - Feng, Miao
AU  - Fernández-Chacón, Rafael
AU  - Fernandez-Cuesta, Irene
AU  - Fertig, Niels
AU  - Förster, Stephan
AU  - Garrido, Jose A.
AU  - George, Michael
AU  - Guse, Andreas H.
AU  - Hampp, Norbert
AU  - Harberts, Jann
AU  - Han, Jili
AU  - Heekeren, Hauke R.
AU  - Hofmann, Ulrich G.
AU  - Holzapfel, Malte
AU  - Hosseinkazemi, Hessam
AU  - Huang, Yalan
AU  - Huber, Patrick
AU  - Hyeon, Taeghwan
AU  - Ingebrandt, Sven
AU  - Ienca, Marcello
AU  - Iske, Armin
AU  - Kang, Yanan
AU  - Kasieczka, Gregor
AU  - Kim, Dae-Hyeong
AU  - Kostarelos, Kostas
AU  - Lee, Jae-Hyun
AU  - Lin, Kai-Wei
AU  - Liu, Sijin
AU  - Liu, Xin
AU  - Liu, Yang
AU  - Lohr, Christian
AU  - Mailänder, Volker
AU  - Maffongelli, Laura
AU  - Megahed, Saad
AU  - Mews, Alf
AU  - Mutas, Marina
AU  - Nack, Leroy
AU  - Nakatsuka, Nako
AU  - Oertner, Thomas G.
AU  - Offenhäusser, Andreas
AU  - Oheim, Martin
AU  - Otange, Ben
AU  - Otto, Ferdinand
AU  - Patrono, Enrico
AU  - Peng, Bo
AU  - Picchiotti, Alessandra
AU  - Pierini, Filippo
AU  - Pötter-Nerger, Monika
AU  - Pozzi, Maria
AU  - Pralle, Arnd
AU  - Prato, Maurizio
AU  - Qi, Bing
AU  - Ramos-Cabrer, Pedro
AU  - Genger, Ute Resch
AU  - Ritter, Norbert
AU  - Rittner, Marten
AU  - Roy, Sathi
AU  - Santoro, Francesca
AU  - Schuck, Nicolas W.
AU  - Schulz, Florian
AU  - Şeker, Erkin
AU  - Skiba, Marvin
AU  - Sosniok, Martin
AU  - Stephan, Holger
AU  - Wang, Ruixia
AU  - Wang, Ting
AU  - Wegner, K. David
AU  - Weiss, Paul S.
AU  - Xu, Ming
AU  - Yang, Chenxi
AU  - Zargarian, Seyed Shahrooz
AU  - Zeng, Yuan
AU  - Zhou, Yaofeng
AU  - Zhu, Dingcheng
AU  - Zierold, Robert
AU  - Parak, Wolfgang J.
TI  - Interfacing with the Brain: How Nanotechnology Can Contribute
JO  - ACS nano
VL  - 19
IS  - 11
SN  - 1936-0851
CY  - Washington, DC
PB  - Soc.
M1  - PUBDB-2025-01098
SP  - 10630 - 10717
PY  - 2025
N1  - R.G. received financial support by the German Research Council (DFG, grant RE 1203/38-1. SIREN)
AB  - Interfacing artificial devices with the human brain is the central goal of neurotechnology. Yet, our imaginations are often limited by currently available paradigms and technologies. Suggestions for brain–machine interfaces have changed over time, along with the available technology. Mechanical levers and cable winches were used to move parts of the brain during the mechanical age. Sophisticated electronic wiring and remote control have arisen during the electronic age, ultimately leading to plug-and-play computer interfaces. Nonetheless, our brains are so complex that these visions, until recently, largely remained unreachable dreams. The general problem, thus far, is that most of our technology is mechanically and/or electrically engineered, whereas the brain is a living, dynamic entity. As a result, these worlds are difficult to interface with one another. Nanotechnology, which encompasses engineered solid-state objects and integrated circuits, excels at small length scales of single to a few hundred nanometers and, thus, matches the sizes of biomolecules, biomolecular assemblies, and parts of cells. Consequently, we envision nanomaterials and nanotools as opportunities to interface with the brain in alternative ways. Here, we review the existing literature on the use of nanotechnology in brain–machine interfaces and look forward in discussing perspectives and limitations based on the authors’ expertise across a range of complementary disciplines─from neuroscience, engineering, physics, and chemistry to biology and medicine, computer science and mathematics, and social science and jurisprudence. We focus on nanotechnology but also include information from related fields when useful and complementary.
LB  - PUB:(DE-HGF)16
C6  - pmid:40063703
UR  - <Go to ISI:>//WOS:001446202200001
DO  - DOI:10.1021/acsnano.4c10525
UR  - https://bib-pubdb1.desy.de/record/625324
ER  -