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@ARTICLE{Simke:593879,
author = {Simke, Florian and Fischer, Paul and Damjanović, Tomislav
and Kádek, Alan and Kierspel, Thomas and Lorenzen, Kristina
and Uetrecht, Charlotte and Schweikhard, Lutz},
title = {{C}ommissioning the digital mass-filter/ion-trap module for
the {MS} {SPIDOC} prototype},
journal = {Journal of Instrumentation},
volume = {18},
number = {10},
issn = {1748-0221},
address = {London},
publisher = {Inst. of Physics},
reportid = {PUBDB-2023-05545},
pages = {P10021},
year = {2023},
abstract = {The combination of a linear quadrupole ion-filter and
linear Paul trap operated with a rectangular guiding field
for the filtering and accumulation of ions within the Mass
Spectrometry for Single Particle Imaging of Dipole Oriented
protein Complexes (MS SPIDOC) prototype [T. Kierspel et al.,
Anal. Bioanal. Chem., published online] is characterized.
Using cationic caesium-iodide clusters, the ion-separation
performance, ion accumulation, cooling, and ejection via
in-trap pin electrodes is evaluated. Furthermore,
proof-of-principle measurements are performed with 64 kDa
multiply-charged non-covalent protein complexes of human
hemoglobin and 804 kDa non-covalent complex of GroEL, to
demonstrate that the module meets the criteria to handle
high-mass ions which are the main objective of the MS SPIDOC
project. The setup's performance is found to be in line with
previous results from ion-trajectory simulations [F. Simke
et al., Int. J. Mass Spectrom.473 (2022) 116779].},
cin = {CSSB-LIV/DESY-CU / $XFEL_E2_SEC$},
ddc = {610},
cid = {$I:(DE-H253)CSSB-LIV_DESY-CU-20220525$ /
$I:(DE-H253)XFEL_E2_SEC-20210408$},
pnm = {633 - Life Sciences – Building Blocks of Life: Structure
and Function (POF4-633) / MS SPIDOC - Mass Spectrometry for
Single Particle Imaging of Dipole Oriented protein Complexes
(801406)},
pid = {G:(DE-HGF)POF4-633 / G:(EU-Grant)801406},
experiment = {EXP:(DE-H253)XFEL-Exp-20150101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:001117781700010},
doi = {10.1088/1748-0221/18/10/P10021},
url = {https://bib-pubdb1.desy.de/record/593879},
}