%0 Journal Article
%A Simke, Florian
%A Fischer, Paul
%A Damjanović, Tomislav
%A Kádek, Alan
%A Kierspel, Thomas
%A Lorenzen, Kristina
%A Uetrecht, Charlotte
%A Schweikhard, Lutz
%T Commissioning the digital mass-filter/ion-trap module for the MS SPIDOC prototype
%J Journal of Instrumentation
%V 18
%N 10
%@ 1748-0221
%C London
%I Inst. of Physics
%M PUBDB-2023-05545
%P P10021 
%D 2023
%X The combination of a linear quadrupole ion-filter and linear Paul trap operated with a rectangular guiding field for the filtering and accumulation of ions within the Mass  Spectrometry for Single Particle Imaging of Dipole  Oriented protein Complexes (MS SPIDOC) prototype [T. Kierspel et al.,  Anal. Bioanal. Chem., published online] is characterized. Using cationic caesium-iodide clusters, the ion-separation performance, ion accumulation, cooling, and ejection via in-trap pin electrodes is evaluated. Furthermore, proof-of-principle measurements are performed with 64 kDa multiply-charged non-covalent protein complexes of human hemoglobin and 804 kDa non-covalent complex of GroEL, to demonstrate that the module meets the criteria to handle high-mass ions which are the main objective of the MS SPIDOC project. The setup's performance is found to be in line with previous results from ion-trajectory simulations [F. Simke et al., Int. J. Mass Spectrom.473 (2022) 116779].  
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:001117781700010
%R 10.1088/1748-0221/18/10/P10021
%U https://bib-pubdb1.desy.de/record/593879