TY - JOUR AU - Fernandez Corral, Alvaro AU - Vogt, Emil AU - Iske, Armin AU - Saleh, Yahya AU - Küpper, Jochen AU - Yachmenev, Andrey TI - Computing Excited States of Molecules Using Normalizing Flows JO - Journal of chemical theory and computation VL - 21 IS - 10 SN - 1549-9618 PB - [Verlag nicht ermittelbar] M1 - PUBDB-2023-05096 M1 - arXiv:2308.16468 SP - 5221 - 5229 PY - 2025 AB - Calculations of highly excited and delocalizedmolecular vibrational states are computationally challenging tasks,which strongly depend on the choice of coordinates for describingvibrational motions. We introduce a new method that leveragesnormalizing flows, i.e, parametrized invertible functions, to learnoptimal vibrational coordinates that satisfy the variational principle.This approach produces coordinates tailored to the vibrational problem at hand, significantly increasing the accuracy and enhancingthe basis set convergence of the calculated energy spectrum. The efficiency of the method is demonstrated in calculations of the 100lowest excited vibrational states of H<sub>2</sub>S, H<sub>2</sub>CO, and HCN/HNC. The method effectively captures the essential vibrational behaviorof molecules by enhancing the separability of the Hamiltonian and hence allows for an effective assignment of approximate quantumnumbers. We demonstrate that the optimized coordinates are transferable across different levels of basis set truncation, enabling acost-efficient protocol for computing vibrational spectra of high-dimensional systems. LB - PUB:(DE-HGF)16 C6 - pmid:40374563 DO - DOI:10.1021/acs.jctc.5c00590 UR - https://bib-pubdb1.desy.de/record/589161 ER -