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@ARTICLE{Mehrabi:582126,
      author       = {Mehrabi, Pedram and Müller-Werkmeister, Henrike M. and
                      Leimkohl, Jan-Philipp and Schikora, Hendrik and Ninkovic,
                      Jelena and Krivokuca, Silvia and Andriček, Ladislav and
                      Epp, Sascha W. and Sherrell, Darren and Owen, Robin L. and
                      Pearson, Arwen R. and Tellkamp, Friedjof and Schulz, Eike
                      and Miller, R. J. Dwayne},
      title        = {{T}he {HARE} chip for efficient time-resolved serial
                      synchrotron crystallography},
      journal      = {Journal of synchrotron radiation},
      volume       = {27},
      number       = {2},
      issn         = {0909-0495},
      address      = {[Erscheinungsort nicht ermittelbar]},
      publisher    = {Wiley-Blackwell},
      reportid     = {PUBDB-2023-01816},
      pages        = {360 - 370},
      year         = {2020},
      abstract     = {Serial synchrotron crystallography (SSX) is an emerging
                      technique for static and time-resolved protein structure
                      determination. Using specifically patterned silicon chips
                      for sample delivery, the `hit-and-return' (HARE) protocol
                      allows for efficient time-resolved data collection. The
                      specific pattern of the crystal wells in the HARE chip
                      provides direct access to many discrete time points. HARE
                      chips allow for optical excitation as well as on-chip mixing
                      for reaction initiation, making a large number of protein
                      systems amenable to time-resolved studies. Loading of
                      protein microcrystals onto the HARE chip is streamlined by a
                      novel vacuum loading platform that allows fine-tuning of
                      suction strength while maintaining a humid environment to
                      prevent crystal dehydration. To enable the widespread use of
                      time-resolved serial synchrotron crystallography (TR-SSX),
                      detailed technical descriptions of a set of accessories that
                      facilitate TR-SSX workflows are provided.},
      cin          = {DOOR ; HAS-User / CFEL-SSUMP / CFEL-SSUUB / UNI/CUI},
      ddc          = {550},
      cid          = {I:(DE-H253)HAS-User-20120731 /
                      I:(DE-H253)CFEL-SSUMP-20160915 /
                      I:(DE-H253)CFEL-SSUUB-20210331 /
                      $I:(DE-H253)UNI_CUI-20121230$},
      pnm          = {6G3 - PETRA III (DESY) (POF4-6G3) / DFG project
                      G:(GEPRIS)194651731 - EXC 1074: Hamburger Zentrum für
                      ultraschnelle Beobachtung (CUI): Struktur, Dynamik und
                      Kontrolle von Materie auf atomarer Skala (194651731)},
      pid          = {G:(DE-HGF)POF4-6G3 / G:(GEPRIS)194651731},
      experiment   = {EXP:(DE-H253)P-P14-20150101},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {32153274},
      UT           = {WOS:000519725000012},
      doi          = {10.1107/S1600577520000685},
      url          = {https://bib-pubdb1.desy.de/record/582126},
}