000582126 001__ 582126
000582126 005__ 20241014220430.0
000582126 0247_ $$2doi$$a10.1107/S1600577520000685
000582126 0247_ $$2ISSN$$a0909-0495
000582126 0247_ $$2ISSN$$a1600-5775
000582126 0247_ $$2datacite_doi$$a10.3204/PUBDB-2023-01816
000582126 0247_ $$2altmetric$$aaltmetric:76768466
000582126 0247_ $$2pmid$$a32153274
000582126 0247_ $$2WOS$$aWOS:000519725000012
000582126 037__ $$aPUBDB-2023-01816
000582126 041__ $$aEnglish
000582126 082__ $$a550
000582126 1001_ $$0P:(DE-H253)PIP1029103$$aMehrabi, Pedram$$b0
000582126 245__ $$aThe HARE chip for efficient time-resolved serial synchrotron crystallography
000582126 260__ $$a[Erscheinungsort nicht ermittelbar]$$bWiley-Blackwell$$c2020
000582126 3367_ $$2DRIVER$$aarticle
000582126 3367_ $$2DataCite$$aOutput Types/Journal article
000582126 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1728908110_4011058
000582126 3367_ $$2BibTeX$$aARTICLE
000582126 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000582126 3367_ $$00$$2EndNote$$aJournal Article
000582126 520__ $$aSerial synchrotron crystallography (SSX) is an emerging technique for static and time-resolved protein structure determination. Using specifically patterned silicon chips for sample delivery, the `hit-and-return' (HARE) protocol allows for efficient time-resolved data collection. The specific pattern of the crystal wells in the HARE chip provides direct access to many discrete time points. HARE chips allow for optical excitation as well as on-chip mixing for reaction initiation, making a large number of protein systems amenable to time-resolved studies. Loading of protein microcrystals onto the HARE chip is streamlined by a novel vacuum loading platform that allows fine-tuning of suction strength while maintaining a humid environment to prevent crystal dehydration. To enable the widespread use of time-resolved serial synchrotron crystallography (TR-SSX), detailed technical descriptions of a set of accessories that facilitate TR-SSX workflows are provided.
000582126 536__ $$0G:(DE-HGF)POF4-6G3$$a6G3 - PETRA III (DESY) (POF4-6G3)$$cPOF4-6G3$$fPOF IV$$x0
000582126 536__ $$0G:(GEPRIS)194651731$$aDFG project G:(GEPRIS)194651731 - EXC 1074: Hamburger Zentrum für ultraschnelle Beobachtung (CUI): Struktur, Dynamik und Kontrolle von Materie auf atomarer Skala (194651731)$$c194651731$$x1
000582126 588__ $$aDataset connected to CrossRef, Journals: bib-pubdb1.desy.de
000582126 693__ $$0EXP:(DE-H253)P-P14-20150101$$1EXP:(DE-H253)PETRAIII-20150101$$6EXP:(DE-H253)P-P14-20150101$$aPETRA III$$fPETRA Beamline P14$$x0
000582126 7001_ $$0P:(DE-H253)PIP1026032$$aMüller-Werkmeister, Henrike M.$$b1
000582126 7001_ $$0P:(DE-H253)PIP1080602$$aLeimkohl, Jan-Philipp$$b2
000582126 7001_ $$0P:(DE-H253)PIP1029493$$aSchikora, Hendrik$$b3
000582126 7001_ $$aNinkovic, Jelena$$b4
000582126 7001_ $$aKrivokuca, Silvia$$b5
000582126 7001_ $$aAndriček, Ladislav$$b6
000582126 7001_ $$0P:(DE-H253)PIP1008052$$aEpp, Sascha W.$$b7
000582126 7001_ $$0P:(DE-H253)PIP1081692$$aSherrell, Darren$$b8
000582126 7001_ $$0P:(DE-H253)PIP1081680$$aOwen, Robin L.$$b9
000582126 7001_ $$0P:(DE-H253)PIP1022042$$aPearson, Arwen R.$$b10
000582126 7001_ $$0P:(DE-H253)PIP1007800$$aTellkamp, Friedjof$$b11
000582126 7001_ $$0P:(DE-H253)PIP1019225$$aSchulz, Eike$$b12$$eCorresponding author
000582126 7001_ $$0P:(DE-H253)PIP1012317$$aMiller, R. J. Dwayne$$b13$$eCorresponding author
000582126 773__ $$0PERI:(DE-600)2021413-3$$a10.1107/S1600577520000685$$gVol. 27, no. 2, p. 360 - 370$$n2$$p360 - 370$$tJournal of synchrotron radiation$$v27$$x0909-0495$$y2020
000582126 8564_ $$uhttps://bib-pubdb1.desy.de/record/582126/files/wz5004.pdf$$yOpenAccess
000582126 8564_ $$uhttps://bib-pubdb1.desy.de/record/582126/files/wz5004.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000582126 909CO $$ooai:bib-pubdb1.desy.de:582126$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1029103$$aCentre for Free-Electron Laser Science$$b0$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1029103$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b0$$kMPG
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1029103$$aExternal Institute$$b0$$kExtern
000582126 9101_ $$0I:(DE-588b)235011-7$$6P:(DE-H253)PIP1026032$$aEuropean Molecular Biology Laboratory$$b1$$kEMBL
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1026032$$aExternal Institute$$b1$$kExtern
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1080602$$aCentre for Free-Electron Laser Science$$b2$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1080602$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b2$$kMPG
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1029493$$aCentre for Free-Electron Laser Science$$b3$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1029493$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b3$$kMPG
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1008052$$aCentre for Free-Electron Laser Science$$b7$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1008052$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b7$$kMPG
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1081692$$aExternal Institute$$b8$$kExtern
000582126 9101_ $$0I:(DE-588)1043621512$$6P:(DE-H253)PIP1081692$$aEuropean XFEL$$b8$$kXFEL.EU
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1081680$$aExternal Institute$$b9$$kExtern
000582126 9101_ $$0I:(DE-588)1043621512$$6P:(DE-H253)PIP1081680$$aEuropean XFEL$$b9$$kXFEL.EU
000582126 9101_ $$0I:(DE-588b)235011-7$$6P:(DE-H253)PIP1022042$$aEuropean Molecular Biology Laboratory$$b10$$kEMBL
000582126 9101_ $$0I:(DE-588)1043621512$$6P:(DE-H253)PIP1022042$$aEuropean XFEL$$b10$$kXFEL.EU
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1022042$$aExternal Institute$$b10$$kExtern
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1007800$$aCentre for Free-Electron Laser Science$$b11$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1007800$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b11$$kMPG
000582126 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1019225$$aExternal Institute$$b12$$kExtern
000582126 9101_ $$0I:(DE-H253)_CFEL-20120731$$6P:(DE-H253)PIP1012317$$aCentre for Free-Electron Laser Science$$b13$$kCFEL
000582126 9101_ $$0I:(DE-588b)2019024-4$$6P:(DE-H253)PIP1012317$$aMax-Planck-Gesellschaft zur Förderung der Wissenschaften$$b13$$kMPG
000582126 9131_ $$0G:(DE-HGF)POF4-6G3$$1G:(DE-HGF)POF4-6G0$$2G:(DE-HGF)POF4-600$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bForschungsbereich Materie$$lGroßgeräte: Materie$$vPETRA III (DESY)$$x0
000582126 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000582126 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000582126 9201_ $$0I:(DE-H253)HAS-User-20120731$$kDOOR ; HAS-User$$lDOOR-User$$x0
000582126 9201_ $$0I:(DE-H253)CFEL-SSUMP-20160915$$kCFEL-SSUMP$$lMPSD$$x1
000582126 9201_ $$0I:(DE-H253)CFEL-SSUUB-20210331$$kCFEL-SSUUB$$lSSU for Ultrafast Beam Applications$$x2
000582126 9201_ $$0I:(DE-H253)UNI_CUI-20121230$$kUNI/CUI$$lbeauftragt von UNI$$x3
000582126 980__ $$ajournal
000582126 980__ $$aVDB
000582126 980__ $$aI:(DE-H253)HAS-User-20120731
000582126 980__ $$aI:(DE-H253)CFEL-SSUMP-20160915
000582126 980__ $$aI:(DE-H253)CFEL-SSUUB-20210331
000582126 980__ $$aI:(DE-H253)UNI_CUI-20121230
000582126 980__ $$aUNRESTRICTED
000582126 9801_ $$aFullTexts