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@ARTICLE{Brmmer:453521,
author = {Brümmer, Theresa and Debus, Alexander and Pausch, Richard
and Osterhoff, Jens and Grüner, Florian},
title = {{D}esign study for a compact laser-driven source for
medical x-ray fluorescence imaging},
journal = {Physical review accelerators and beams},
volume = {23},
number = {3},
issn = {2469-9888},
address = {College Park, MD},
publisher = {American Physical Society},
reportid = {PUBDB-2020-05317},
pages = {031601},
year = {2020},
abstract = {Thomson scattering sources with their hard x-ray pencil
beams represent a promising candidate to
drivehigh-resolution X-ray Fluorescence Imaging (XFI). As
XFI is a scanning imaging modality, it specificallyrequires
pencil-beam geometries along with a high beam mobility. In
combination with laser-wakefieldacceleration (LWFA) such
sources could provide the compactness needed for a future
transition intoclinical application. A sufficient flux
within a small bandwidth could enable in-vivo
high-sensitivity XFIfor early cancer diagnostics and
pharmacokinetic imaging. We thus report on a specific
all-laser drivensource design directed at increasing the
photon number within the bandwidth and opening angle defined
byXFI conditions. Typical parameters of driver lasers and
electron bunches from LWFA are utilized andcontrolled within
realistic parameter regions on the basis of appropriate beam
optics. An active plasma lensis implemented for chromatic
focal control of the bunch. Source performance limits are
identified andcompared to existing x-ray sources with regard
to their potential to be implemented in future clinical
XFI.},
keywords = {Design Studies (autogen)},
cin = {FLA / MPA / CFEL-NOVA},
ddc = {530},
cid = {I:(DE-H253)FLA-20120731 / I:(DE-H253)MPA-20200816 /
I:(DE-H253)CFEL-NOVA-20160909},
pnm = {631 - Accelerator R $\&$ D (POF3-631) / PWA - Research
group for plasma-based accelerators (PWA-20150304)},
pid = {G:(DE-HGF)POF3-631 / G:(DE-H253)PWA-20150304},
experiment = {EXP:(DE-H253)FLASHForward-20150101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000517431500001},
doi = {10.1103/PhysRevAccelBeams.23.031601},
url = {https://bib-pubdb1.desy.de/record/453521},
}