Poster

PUBDB-2019-04567

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Design Study of a Laser-driven X-ray Source for Medical Imaging

Bruemmer, T. K. (Corresponding author)CFEL*Extern*DESY* ; Bohlen, S.DESY* ; Poder, K.DESY* ; Staufer, T.Extern* ; Gruener, F.CFEL*Extern* ; Osterhoff, J.DESY*

2019

Abstract: The combination of laser-wakefield acceleration and Thomsonscattering (TS) driven by one high-power laser allows for all-opticalbrilliant X-ray sources of compact design. Such source designs enablethe clinical implementation of X-ray-based medical imaging modalitiessuch as X-ray fluorescence imaging (XFI). XFI offers the in-vivolocalization of functionalized gold nanoparticles (GNPs) with highsensitivity, temporal and spatial resolution at low dose exposure. Thisrequires hard X-ray sources (~100 keV) of specific design parameters,i.e. a pencil-shaped X-ray beam within a small bandwidth and a highphoton flux to achieve feasible exposure times. Thus, optimization ofthe TS process is required to enhance the X-ray source to fulfill thegiven criteria. In this poster we show the techniques employed for thedetermination of the best laser and electron parameters. The designconcept and simulation results for a first proof-of-principle experimentare presented. Electron focusing via an active plasma lens allows forsingle-element symmetric focusing on the one hand. On the other handX-ray bandwidth control for broadband electron energy spectra (no energyspread limit) is achieved.

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Contributing Institute(s):

1. Forschung Linear Accelerator (FLA)
2. beautragt von UNI/EXP (CFEL-NOVA)
3. Uni Hamburg / Experimentalphysik (UNI/EXP)

Research Program(s):

1. 631 - Accelerator R & D (POF3-631) (POF3-631)
2. PWA - Research group for plasma-based accelerators (PWA-20150304) (PWA-20150304)

Experiment(s):

1. FLASHForward

Appears in the scientific report 2019

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