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@ARTICLE{McDougall:418925,
author = {McDougall, Matthew and McEleney, Kevin and Francisco, Olga
and Trieu, Benchmen and Ogbomo, Efehi Kelly and Tomy, Gregg
and Stetefeld, Jörg},
title = {{R}eductive power of the archaea right-handed coiled coil
nanotube ({RHCC}-{NT}) and incorporation of mercury clusters
inside protein cages},
journal = {Journal of structural biology},
volume = {203},
number = {3},
issn = {1047-8477},
address = {San Diego, Calif.},
publisher = {Elsevier},
reportid = {PUBDB-2019-00829},
pages = {281 - 287},
year = {2018},
note = {© Elsevier Inc.},
abstract = {Coiled coils are well described as powerful oligomerization
motifs and exhibit a large diversity of functions, including
gene regulation, cell division, membrane fusion and drug
extrusion. The archaea S-layer originated right-handed
coiled coil –RHCC-NT- is characterized by extreme
stability and is free of cysteine and histidine moieties. In
the current study, we have followed a multidisciplinary
approach to investigate the capacity of RHCC-NT to bind a
variety of ionic complex metal ions. At the outside of the
RHCC-NT, one mercury ion forms an electrostatic interaction
with the S-methyl moiety of the single methionine residue
present in each coil. We demonstrate that RHCC-NT is
reducing and incorporating metallic mercury in the
large-sized interior cavities which are lined up along the
tetrameric channel.},
cin = {DOOR},
ddc = {540},
cid = {I:(DE-H253)HAS-User-20120731},
pnm = {899 - ohne Topic (POF3-899)},
pid = {G:(DE-HGF)POF3-899},
experiment = {EXP:(DE-H253)D-BW7-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29879486},
UT = {WOS:000442713100012},
doi = {10.1016/j.jsb.2018.05.013},
url = {https://bib-pubdb1.desy.de/record/418925},
}