%0 Journal Article
%A Hubčík, Lukáš
%A Galliková, Dominika
%A Pullmannová, Petra
%A Lacinová, Ľubica
%A Sulová, Zdena
%A Hanulová, Mária
%A Funari, Sergio de Souza
%A Devínsky, Ferdinand
%A Uhríková, Daniela
%T DNA–DOPE–gemini surfactants complexes at low surface charge density: from structure to transfection efficiency
%J General physiology and biophysics
%V 37
%N 1
%@ 1338-4325
%C Bratislava
%I AEPress
%M PUBDB-2019-00177
%P 57 - 69
%D 2018
%Z © AEPress s.r.o
%X DNA condensation, structure and transfection efficiency of complexes formed by gemini surfactants alkane-α,ω-diyl-bis(dodecyldimethylammonium bromide)s (CnGS12, n = 3, 6 and 12 is the number of alkane spacer carbons), dioleoylphosphatidylethanolamine (CnGS12/DOPE = 0.3 mol/mol) and DNA at low surface charge density were investigated through different techniques. Small angle X-ray diffraction showed a condensed lamellar phase with marked dependence of DNA-DNA distance on (+/-) charge ratio. High ionic strength of hydrating medium screens the interaction DNA - CnGS12/DOPE and complexed DNA represented maximally   45–60
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29424352
%U <Go to ISI:>//WOS:000425206200006
%R 10.4149/gpb_2017042
%U https://bib-pubdb1.desy.de/record/418090