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@ARTICLE{Chung:418080,
author = {Chung, Hsiang-Yu and Greinert, Rüdiger and Kärtner, Franz
X. and Chang, Guoqing},
title = {{M}ultimodal imaging platform for optical virtual skin
biopsy enabled by a fiber-based two-color ultrafast laser
source},
journal = {Biomedical optics express},
volume = {10},
number = {2},
issn = {2156-7085},
address = {Washington, DC},
publisher = {OSA},
reportid = {PUBDB-2019-00167},
pages = {514 - 525},
year = {2019},
abstract = {We demonstrate multimodal label-free nonlinear optical
microscopy in human skin enabled by a fiber-based two-color
ultrafast source. Energetic femtosecond pulses at 775 nm and
1250 nm are simultaneously generated by an Er-fiber laser
source employing frequency doubling and self-phase
modulation enabled spectral selection. The integrated
nonlinear optical microscope driven by such a two-color
femtosecond source enables the excitation of endogenous
two-photon excitation fluorescence, second-harmonic
generation, and third-harmonic generation in human skin.
Such a 3-channel imaging platform constitutes a powerful
tool for clinical application and optical virtual skin
biopsy.},
cin = {FS-CFEL-2},
ddc = {610},
cid = {I:(DE-H253)FS-CFEL-2-20120731},
pnm = {6211 - Extreme States of Matter: From Cold Ions to Hot
Plasmas (POF3-621) / VH-NG-804 - Towards Laboratory-Based
Ultrafast Bright EUV and X-ray Sources
$(2015_IVF-VH-NG-804)$ / VH-VI-419 - Dynamic Pathways in
Multidimensional Landscapes (VH-VI-419) / HCJRG-201 -
Advanced Laser Technologies for Ultrafast Spectroscopy of
Quantum Materials $(2015_IFV-HCJRG-201)$ / CUI - Hamburger
Zentrum für ultraschnelle Beobachtung (194651731)},
pid = {G:(DE-HGF)POF3-6211 / $G:(DE-HGF)2015_IVF-VH-NG-804$ /
G:(DE-HGF)VH-VI-419 / $G:(DE-HGF)2015_IFV-HCJRG-201$ /
G:(GEPRIS)194651731},
experiment = {EXP:(DE-MLZ)NOSPEC-20140101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30800496},
UT = {WOS:000457500300010},
doi = {10.1364/BOE.10.000514},
url = {https://bib-pubdb1.desy.de/record/418080},
}