Home > Publications database > Energetic Ultrafast Fiber Laser Scources Tunable in 1030-1215 nm for Deep Tissue Multi-Photon Microscopy > print

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100 1 _ |a Liu, Wei
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245 _ _ |a Energetic Ultrafast Fiber Laser Scources Tunable in 1030-1215 nm for Deep Tissue Multi-Photon Microscopy
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520 _ _ |a We demonstrate an energy scalable approach to implement ultrafast fiber laser sources suitable for deep tissue multi-photon microscopy imaging. Enabled by fiber-opticnonlinearities (dominated by self-phase modulation), these unique ultrafast sources produce nearly transform-limited pulses of 50-90 fs in duration with the center wavelength tunable inthe wavelength range of 1030-1215 nm. The resulting pulse energy can be scaled up to 20 nJ by optimizing fiber dispersion, shortening fiber length, and using large-mode-area fibers. Weapplied such an energetic source to a proof-of-principle study of ex vivo human skin based on harmonics (i.e., second-harmonic generation and third-harmonic generation) imaging. Thisnew type of fiber-format energetic ultrafast source provides a robust solution for multiphoton microscopy applications.
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700 1 _ |a Chang, Guoqing Noah
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700 1 _ |a Chia, Shih-Hsuan
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700 1 _ |a Chung, Hsiang-Yu
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700 1 _ |a Kärtner, Franz
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700 1 _ |a Greinert, Rüdiger
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773 _ _ |a 10.1364/OE.25.006822
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