000311539 001__ 311539 000311539 005__ 20250717104714.0 000311539 0247_ $$2doi$$a10.1038/sdata.2016.61 000311539 0247_ $$2WOS$$aWOS:000390225400006 000311539 0247_ $$2pmid$$apmid:27479842 000311539 0247_ $$2openalex$$aopenalex:W2487826660 000311539 037__ $$aPUBDB-2016-04849 000311539 041__ $$aEnglish 000311539 082__ $$a610 000311539 1001_ $$aHantke, Max F.$$b0 000311539 245__ $$aA data set from flash X-ray imaging of carboxysomes 000311539 260__ $$aLondon$$bNature Publ. Group$$c2016 000311539 3367_ $$2DRIVER$$aarticle 000311539 3367_ $$2DataCite$$aOutput Types/Journal article 000311539 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1479898197_27378 000311539 3367_ $$2BibTeX$$aARTICLE 000311539 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000311539 3367_ $$00$$2EndNote$$aJournal Article 000311539 520__ $$aUltra-intense femtosecond X-ray pulses from X-ray lasers permit structural studies on single particles and biomolecules without crystals. We present a large data set on inherently heterogeneous, polyhedral carboxysome particles. Carboxysomes are cell organelles that vary in size and facilitate up to 40% of Earth’s carbon fixation by cyanobacteria and certain proteobacteria. Variation in size hinders crystallization. Carboxysomes appear icosahedral in the electron microscope. A protein shell encapsulates a large number of Rubisco molecules in paracrystalline arrays inside the organelle. We used carboxysomes with a mean diameter of 115±26 nm from Halothiobacillus neapolitanus. A new aerosol sample-injector allowed us to record 70,000 low-noise diffraction patterns in 12 min. Every diffraction pattern is a unique structure measurement and high-throughput imaging allows sampling the space of structural variability. The different structures can be separated and phased directly from the diffraction data and open a way for accurate, high-throughput studies on structures and structural heterogeneity in biology and elsewhere. 000311539 536__ $$0G:(DE-HGF)POF3-6215$$a6215 - Soft Matter, Health and Life Sciences (POF3-621)$$cPOF3-621$$fPOF III$$x0 000311539 588__ $$aDataset connected to CrossRef 000311539 693__ $$0EXP:(DE-MLZ)External-20140101$$5EXP:(DE-MLZ)External-20140101$$eMeasurement at external facility$$x0 000311539 7001_ $$aHasse, Dirk$$b1 000311539 7001_ $$0P:(DE-H253)PIP1007725$$aEkeberg, Tomas$$b2 000311539 7001_ $$aJohn, Katja$$b3 000311539 7001_ $$aSvenda, Martin$$b4 000311539 7001_ $$0P:(DE-H253)PIP1013332$$aLoh, Duane$$b5 000311539 7001_ $$aMartin, Andrew V.$$b6 000311539 7001_ $$aTimneanu, Nicusor$$b7 000311539 7001_ $$aLarsson, Daniel S. D.$$b8 000311539 7001_ $$avan der Schot, Gijs$$b9 000311539 7001_ $$aCarlsson, Gunilla H.$$b10 000311539 7001_ $$aIngelman, Margareta$$b11 000311539 7001_ $$aAndreasson, Jakob$$b12 000311539 7001_ $$aWestphal, Daniel$$b13 000311539 7001_ $$aIwan, Bianca$$b14 000311539 7001_ $$0P:(DE-H253)PIP1014042$$aUetrecht, Charlotte$$b15 000311539 7001_ $$0P:(DE-H253)PIP1020945$$aBielecki, Johan$$b16 000311539 7001_ $$0P:(DE-H253)PIP1007507$$aLiang, Mengning$$b17 000311539 7001_ $$0P:(DE-H253)PIP1011192$$aStellato, Francesco$$b18 000311539 7001_ $$0P:(DE-H253)PIP1008249$$aDePonte, Daniel P.$$b19 000311539 7001_ $$0P:(DE-H253)PIP1014119$$aBari, Sadia$$b20 000311539 7001_ $$aHartmann, Robert$$b21 000311539 7001_ $$aKimmel, Nils$$b22 000311539 7001_ $$aKirian, Richard A.$$b23 000311539 7001_ $$aSeibert, M. Marvin$$b24 000311539 7001_ $$aMühlig, Kerstin$$b25 000311539 7001_ $$aSchorb, Sebastian$$b26 000311539 7001_ $$aFerguson, Ken$$b27 000311539 7001_ $$0P:(DE-H253)PIP1007475$$aBostedt, Christoph$$b28 000311539 7001_ $$aCarron, Sebastian$$b29 000311539 7001_ $$aBozek, John D.$$b30 000311539 7001_ $$aRolles, Daniel$$b31 000311539 7001_ $$aRudenko, Artem$$b32 000311539 7001_ $$aFoucar, Lutz$$b33 000311539 7001_ $$0P:(DE-H253)PIP1008052$$aEpp, Sascha$$b34 000311539 7001_ $$0P:(DE-H253)PIP1006324$$aChapman, Henry N.$$b35 000311539 7001_ $$aBarty, Anton$$b36 000311539 7001_ $$aAndersson, Inger$$b37 000311539 7001_ $$aHajdu, Janos$$b38 000311539 7001_ $$0P:(DE-HGF)0$$aMaia, Filipe R. N. 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