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@ARTICLE{Klacsov:207189,
      author       = {Klacsová, Mária and Karlovská, Janka and Uhríková,
                      Daniela and Funari, Sergio de Souza and Balgavý, Pavol},
      title        = {{P}hase {B}ehavior of the {DOPE} + {DOPC} + {A}lkanol
                      {S}ystem},
      journal      = {Soft matter},
      volume       = {10},
      number       = {31},
      issn         = {1744-6848},
      address      = {London},
      publisher    = {Royal Soc. of Chemistry},
      reportid     = {PUBDB-2015-01173},
      pages        = {5842 - 5848},
      year         = {2014},
      note         = {(c) The Royal Society of Chemistry. Post referee full text
                      in progress.},
      abstract     = {Small- and wide-angle X-ray diffraction was used to study
                      the effect of 1-alkanols, as simple models of general
                      anesthetics, (abbreviation $C_{n}OH$, n = 8–18 is the even
                      number of carbons in the aliphatic chain) on the lamellar to
                      hexagonal $L\alpha \rightarrow H_{II}$ phase transition in
                      the
                      dioleoylphosphatidylethanolamine–dioleoylphosphatidylcholine
                      = 3 : 1 mol/mol (DOPE + DOPC) system. All studied $C_{n}OHs$
                      were found to decrease the phase transition temperature of
                      the DOPE + DOPC system in a $C_{n}OH$ chain length and
                      concentration dependent manner and thus promote the
                      formation of the $H_{II}$ phase. Anesthetically active
                      $C_{8}OH$ and $C_{10}OH$ were found to decrease the lattice
                      parameter $\mathit{d}$ of the $L\alpha$ phase, however
                      longer non-anesthetic CnOHs increased the parameter
                      $\mathit{d}$; this effect being more pronounced with
                      increasing $C_{n}OH$ concentration. The lattice parameter
                      $\mathit{a}$ of the $H_{II}$ phase was decreased in the
                      presence of all $C_{n}OHs$, even at the lowest
                      concentrations studied. In the scope of the indirect
                      mechanism of general anesthesia observed changes in the
                      lattice parameter $\mathit{d}$ (reflecting changes in the
                      bilayer thickness) due to the intercalation of $C_{8}OH$ and
                      $C_{10}OH$ might induce changes in the activity of integral
                      membrane proteins engaged in neuronal pathways.},
      cin          = {DOOR / FS-DO / FS-PEX},
      ddc          = {530},
      cid          = {I:(DE-H253)HAS-User-20120731 / I:(DE-H253)FS-DO-20120731 /
                      I:(DE-H253)FS-PEX-20130206},
      pnm          = {DORIS Beamline A2 (POF2-54G13)},
      pid          = {G:(DE-H253)POF2-A2-20130405},
      experiment   = {EXP:(DE-H253)D-A2-20150101},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000340428700021},
      pubmed       = {pmid:24980804},
      doi          = {10.1039/C4SM00530A},
      url          = {https://bib-pubdb1.desy.de/record/207189},
}