Contribution to a conference proceedings/Contribution to a book

PUBDB-2015-00377

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Tumors in murine brains studied by grating-based phase contrast microtomography

Schulz, G.>Extern* ; Dominietto, M.>Extern* ; Kovacs, Z. ; Schmitz, R. ; Hieber, S.>Extern* ; Thalmann, P.>Extern* ; Beckmann, F.>Extern* ; Müller, B.>Extern*

2014

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Please use a persistent id in citations: doi:10.1117/12.2060544

Abstract: Angiogenesis, i.e. the formation of vessels, is one of the key processes during tumor development. The newly formed vessels transport oxygen and nutrients from the healthy tissue to the tumor and gives tumor cells the possibility to replicate. The principle of anti-angiogenic therapy is to block angiogenic process in order to stop tumor growth. The aim of the present study is the investigation of murine glioma vascular architecture at early (7 days), intermediate (10 and 15 days) and late (23 days) stage of growth by means of grating-based phase contrast microtomography. We demonstrate that this technique yields premium contrast between healthy and cancerous parts of murine brain tissues

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Contributing Institute(s):

1. DOOR-User (DOOR)
2. Zentrum für Material- und Küstenforschung (HZG)

Research Program(s):

1. DORIS Beamline W2 (POF2-54G13) (POF2-54G13)

Experiment(s):

1. DORIS Beamline W2 (DORIS III)

Appears in the scientific report 2014

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