%0 Journal Article
%A Pullmannova, P.
%A Funari, S. S.
%A Devinsky, F.
%A Uhrikova, D.
%A DESY
%T The DNA-DNA spacing in gemini surfactants-DOPE-DNA complexes
%J Biochimica et biophysica acta / Biomembranes
%V 1818
%@ 0005-2736
%C Amsterdam
%I Elsevier
%M PHPPUBDB-24709
%P 2725-2731
%D 2012
%X Gemini surfactants from the homologous series of alkane-α,ω-diyl-bis(dodecyldimethylammonium bromide) (CnCS12, number of spacer carbons n=2-12) and dioleoylphosphatidylethanolamine (DOPE) were used for cationic liposome (CL) preparation. CLs condense highly polymerized DNA creating complexes. Small-angle X-ray diffraction identified them as condensed lamellar phase L(α)(C) in the studied range of molar ratios CnGS12/DOPE in the temperature range 20-60°C. The DNA-DNA distance (d(DNA)) is studied in dependence to CnGS12 spacer length and membrane surface charge density. The high membrane surface charge densities (CnGS12/DOPE=0.35 and 0.4mol/mol) lead to the linear dependence of d(DNA) vs. n correlating with the interfacial area of the CnGS12 molecule.
%K DNA: chemistry
%K Phosphatidylethanolamines: chemistry
%K Scattering, Small Angle
%K Surface-Active Agents: chemistry
%K X-Ray Diffraction
%K 1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine (NLM Chemicals)
%K Phosphatidylethanolamines (NLM Chemicals)
%K Surface-Active Agents (NLM Chemicals)
%K DNA (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:22634275
%U <Go to ISI:>//WOS:000309081700026
%R 10.1016/j.bbamem.2012.05.021
%U https://bib-pubdb1.desy.de/record/140072