2024-04-24 16:34 |
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2024-04-24 16:22 |
[PUBDB-2024-01587]
Journal Article
Mpakali, A. ; Barla, I. ; Lu, L. ; et al
Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase
Inhibition of Insulin-Regulated Aminopeptidase is being actively explored for the treatment of several human diseases and several classes of inhibitors have been developed although no clinical applications have been reported yet. Here, we combine enzymological analysis with x-ray crystallography to investigate the mechanism employed by two of the most studied inhibitors of IRAP, an aryl sulfonamide and a 2-amino-4H-benzopyran named HFI-419. [...]
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2024-04-24 16:05 |
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2024-04-24 15:04 |
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2024-04-24 14:23 |
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2024-04-23 14:43 |
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2024-04-18 11:22 |
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2024-04-15 11:17 |
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2024-04-11 15:58 |
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2024-04-10 09:39 |
[PUBDB-2024-01388]
Journal Article
Wong, K.-F. ; Li, W. ; Wang, Z. ; et al
Far-field Petahertz Sampling of Plasmonic Fields
The response of metal nanostructures to optical excitation leads to localized surface plasmon (LSP) generation with nanoscale field confinement driving applications in, for example,quantum optics and nanophotonics. Field sampling in the terahertz domain has had a tremendous impact on the ability to trace such collective excitations. [...]
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