Journal of medicinal chemistry
	Common abbreviations: J. Med. Chem. [DE-600] JMC [DE-600] J Med Pharm Chem [iso] J Med Chem [iso] J Med Chem [dnlm] J Med Chem [iso]

Type:	journal
DDC:	610
Keywords(s):	Klinische Chemie, Zeitschrift, Online-Ressource, Physiologische Chemie, Zeitschrift, Online-Ressource, Physiologische Chemie, Klinische Chemie, Drug Discovery, Molecular Medicine, Organic Chemistry
CODEN:	JMCMA
ISSN(s):	0022-2623, 0095-9065, 1520-4804, 1943-2992
Publisher:	ACS : Washington, DC 1959-
Country:	United States of America
Appears:	print, online
ID:	PERI:(DE-600)1491411-6

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Chemical Reactions ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; Index Chemicus ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

Recent Publications

All known publications ...
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http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Hernandez-Olmos, V. ; Patzke, J. V. ; Stone, C. E. ; Nair, R. K. ; Weller, K. ; Sauer, F. ; Endres, E. ; Jamai, O. ; Rachor, L. ; Warmutz, C. H. ; Schwalm, M. P. ; Mitrovic, M. ; Grenier, V. ; Ehrler, J. H. M. ; Proschak, A. ; Heering, J. ; Sotriffer, C. ; Mulder, M. P. C. ; Knapp, S. ; Kisker, C. ; Proschak, E. (Corresponding author)
Structure Merging Approach Leads to New Dual Potent and Selective USP25/USP28 Inhibitors
Journal of medicinal chemistry xx, acs.jmedchem.5c03045 (2026) [10.1021/acs.jmedchem.5c03045]2026     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Beck, H. (Corresponding author) ; Mesch, S. (Corresponding author) ; Zimmermann, S. ; Vakalopoulos, A. ; Lehmann, L. ; Gericke, K. M. ; Süßmeier, F. ; Baerfacker, L. ; Hillisch, A. ; Meier, K. ; Tersteegen, A. ; Buchmüller, A. ; Gerdes, C. ; Dietze-Torres, J. ; Kersten, E. ; Partikel, K. ; Bröhl, A. ; Levilain, G. ; Heitmeier, S. ; Pfaff, N. ; Follmann, M.
Discovery of BAY 3389934 Hydrochloride: A Potent and Selective Small-Molecule Dual Factor IIa/Xa Inhibitor with Short Half-Life for the Acute Treatment of Sepsis-Induced Coagulopathy
Journal of medicinal chemistry 68(12), 12687 - 12707 (2025) [10.1021/acs.jmedchem.5c00538]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Milgram, B. C. (Corresponding author) ; Borrelli, D. R. ; Brooijmans, N. ; Henderson, J. A. ; Hilbert, B. J. ; Huff, M. R. ; Ito, T. ; Jackson, E. L. ; Jonsson, P. ; Ladd, B. ; O’Hearn, E. L. ; Pagliarini, R. A. ; Roberts, S. A. ; Ronseaux, S. ; Stuart, D. D. ; Wang, W. ; Guzman-Perez, A.
Discovery of STX-721, a Covalent, Potent, and Highly Mutant-Selective EGFR/HER2 Exon20 Insertion Inhibitor for the Treatment of Non-Small Cell Lung Cancer
Journal of medicinal chemistry 68(3), 2403 - 2421 (2025) [10.1021/acs.jmedchem.4c02377]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Vaškevičius, A. ; Žvirblis, M. ; Kurtenoka, M. ; Leitans, J. ; Manakova, E. ; Paketurytė-Latvė, V. ; Kvietkauskaitė, A. ; Kazaks, A. ; Eimonta, V. ; Čerepenkaitė, K. ; Kazokaitė-Adomaitienė, J. ; Mickevičiu̅tė, A. ; Juozapaitienė, V. ; Tars, K. ; Gražulis, S. ; Matulienė, J. ; Dudutienė, V. ; Shubin, K. ; Matulis, D. ; Zubrienė, A. (Corresponding author)
Di- meta -Substituted Fluorinated Benzenesulfonamides as Potent and Selective Anticancer Inhibitors of Carbonic Anhydrase IX and XII
Journal of medicinal chemistry 68(17), 18389 - 18406 (2025) [10.1021/acs.jmedchem.5c01142]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Nawa, F. ; Kardanov, A. ; Kasch, T. ; Lewandowski, M. ; Wein, T. ; Höfner, G. ; Marschner, J. A. ; Morozov, V. ; Merk, D. (Corresponding author)Extern*EMBL*
Development of an RXR Agonist Scaffold with Pronounced Homodimer Preference
Journal of medicinal chemistry 68(15), 16172 - 16187 (2025) [10.1021/acs.jmedchem.5c01090]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Pérez Carrillo, V. H. ; Whittaker, J. J. ; Wiedemann, C. ; Harder, J.-M. ; Lohr, T. ; Jamithireddy, A. K. ; Dajka, M. ; Goretzki, B. ; Joseph, B. ; Guskov, A. ; Harmer, N. J. ; Holzgrabe, U. ; Hellmich, U. (Corresponding author)Extern*EMBL*
Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors
Journal of medicinal chemistry 68(5), 5926 - 5941 (2025) [10.1021/acs.jmedchem.5c00134]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Flury, P. ; Krüger, N. ; Sylvester, K. ; Breidenbach, J. ; Al Hamwi, G. ; Qiao, J. ; Chen, Y. ; Rocha, C. ; Serafim, M. S. M. ; Barbosa da Silva, E. ; Pöhlmann, S. ; Poso, A. ; Kronenberger, T. ; Rox, K. ; O’Donoghue, A. J. ; Yang, S. ; Straeter, N.Extern* ; Gütschow, M. ; Laufer, S. A. ; Müller, C. E. ; Pillaiyar, T. (Corresponding author)
Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity
Journal of medicinal chemistry 68(3), 3626 - 3652 (2025) [10.1021/acs.jmedchem.4c02254]2025     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Kirschner, H. ; Heister, N. ; Zouatom, M. ; Zhou, T. ; Hofmann, E.Extern* ; Scherkenbeck, J. ; Stoll, R. (Corresponding author)
Toward More Selective Antibiotic Inhibitors: A Structural View of the Complexed Binding Pocket of E. coli Peptide Deformylase
Journal of medicinal chemistry 67(8), 6384-6396 (2024) [10.1021/acs.jmedchem.3c02382]2024     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Falke, S. (Corresponding author)CFEL*EMBL*DESY* ; Lieske, J.CFEL*XFEL.EU*DESY* ; Herrmann, A. ; Loboda, J. ; Karničar, K. ; Guenther, S.CFEL*XFEL.EU*DESY* ; Reinke, P.CFEL*DESY* ; Ewert, W.CFEL*EMBL*DESY* ; Usenik, A. ; Lindič, N. ; Sekirnik, A. ; Dretnik, K. ; Tsuge, H. ; Turk, V. ; Chapman, H. N.CFEL*XFEL.EU*DESY* ; Hinrichs, W. ; Ebert, G. ; Turk, D. (Corresponding author) ; Meents, A. (Corresponding author)CFEL*XFEL.EU*DESY*
Structural elucidation and antiviral activity of covalent cathepsin L inhibitors
Journal of medicinal chemistry 67(9), 7048-7067 (2024) [10.1021/acs.jmedchem.3c02351]2024     Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Czestkowski, W. ; Krzemiński, Ł. ; Piotrowicz, M. C. ; Mazur, M. ; Pluta, E. ; Andryianau, G. ; Koralewski, R. ; Matyszewski, K. ; Olejniczak, S. ; Kowalski, M. ; Lisiecka, K. ; Kozieł, R. ; Piwowar, K. ; Papiernik, D. ; Nowotny, M. ; Napiórkowska-Gromadzka, A. ; Nowak, E. ; Niedziałek, D. ; Wieczorek, G. ; Siwińska, A. ; Rejczak, T. ; Jędrzejczak, K. ; Mulewski, K. ; Olczak, J. ; Zasłona, Z. ; Gołębiowski, A. ; Drzewicka, K. ; Bartoszewicz, A. (Corresponding author)
Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1
Journal of medicinal chemistry 67(5), 3959-3985 (2024) [10.1021/acs.jmedchem.3c02255]2024     Files  Fulltext BibTeX | EndNote: XML, Text | RIS

All known publications ...
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