% IMPORTANT: The following is UTF-8 encoded. This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.
@ARTICLE{Bertini:94201,
author = {Bertini, I. and Fragai, M. and Luchinat, C. and Melikian,
M. and Mylonas, E. and Sarti, N. and Svergun, D. I. and
DESY},
title = {{I}nterdomain flexibility in full-length matrix
metalloproteinase-1 ({MMP}-1)},
journal = {The journal of biological chemistry},
volume = {284},
issn = {0021-9258},
address = {Bethesda, Md.},
publisher = {Soc.},
reportid = {PHPPUBDB-11922},
pages = {12821-12828},
year = {2009},
abstract = {The presence of extensive reciprocal conformational freedom
between the catalytic and the hemopexin-like domains of
full-length matrix metalloproteinase-1 (MMP-1) is
demonstrated by NMR and small angle x-ray scattering
experiments. This finding is discussed in relation to the
essentiality of the hemopexin-like domain for the
collagenolytic activity of MMP-1. The conformational freedom
experienced by the present system, having the shortest
linker between the two domains, when compared with similar
findings on MMP-12 and MMP-9 having longer and the longest
linker within the family, respectively, suggests this type
of conformational freedom to be a general property of all
MMPs.},
keywords = {Catalysis / Crystallography, X-Ray / Heme / Humans / Matrix
Metalloproteinase 1: chemistry / Matrix Metalloproteinase 1:
metabolism / Matrix Metalloproteinase 12: chemistry / Matrix
Metalloproteinase 9: chemistry / Models, Molecular / Nuclear
Magnetic Resonance, Biomolecular / Pliability / Protein
Conformation / Protein Structure, Tertiary / Recombinant
Proteins: chemistry / Recombinant Proteins: metabolism /
Recombinant Proteins (NLM Chemicals) / Heme (NLM Chemicals)
/ Matrix Metalloproteinase 9 (NLM Chemicals) / Matrix
Metalloproteinase 12 (NLM Chemicals) / Matrix
Metalloproteinase 1 (NLM Chemicals)},
cin = {EMBL},
ddc = {570},
cid = {$I:(DE-H253)EMBL_-2012_-20130307$},
pnm = {FS Beamline without reference (POF1-550)},
pid = {G:(DE-H253)POF1-No-Ref-20130405},
experiment = {EXP:(DE-H253)Unknown-BL-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19282283},
pmc = {pmc:PMC2676012},
UT = {WOS:000265688300027},
doi = {10.1074/jbc.M809627200},
url = {https://bib-pubdb1.desy.de/record/94201},
}