Home > Publications database > Pelizaeus Merzbacher Disease: Morphological Analysis of the Vestibulo-cochlear System > print

001     87375
005     20250731122217.0
024 7 _ |2 pmid
|a pmid:19922087
024 7 _ |2 ISSN
|a 1651-2553
024 7 _ |2 ISSN
|a 0001-6489
024 7 _ |2 ISSN
|a 1651-2251
024 7 _ |2 ISSN
|a 0365-5237
024 7 _ |2 ISSN
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024 7 _ |2 doi
|a 10.3109/00016480802698866
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041 _ _ |a eng
082 _ _ |a 610
100 1 _ |0 P:(DE-HGF)0
|a Schmutzhard, J.
|b 0
110 1 _ |a DESY
|b Experiments with synchrotron radiation
245 _ _ |a Pelizaeus Merzbacher Disease: Morphological Analysis of the Vestibulo-cochlear System
260 _ _ |a Stockholm
|b Informa Healthcare
|c 2009
300 _ _ |a 1395 - 1399
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|s 1482245880_17729
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|a ARTICLE
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|a Journal Article
440 _ 0 |0 PERI:(DE-600)1484331-6
|a Acta Oto Laryngol.
|v 129
|x 0001-6489
|y 12
500 _ _ |3 Converted on 2013-05-30 12:57
|a (c) Informa UK Limited. Post referee full text in progress (embargo 1 year from 18 Nov 2009).
500 _ _ |3 Converted on 2013-06-21 19:20
520 _ _ |a In agreement with previously published findings, our results demonstrate that Pelizaeus Merzbacher disease (PMD) does not affect the development and morphology of the peripheral vestibulo-cochlear system.PMD is a consequence of X-linked mutation of the main central nervous system (CNS) myelin protein resulting in a complex neurological syndrome. Otorhinolaryngological symptoms include nystagmus and alterations of auditory-evoked brainstem responses. To date no histopathological analysis of the inner ear has been performed.The temporal bone morphology of an affected fetus was examined with light microscopy and synchrotron radiation-based micro computed tomography.The regular structure of the vestibulo-cochlear system was shown in this multi-modular analysis.
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650 _ 2 |2 MeSH
|a Aborted Fetus: pathology
650 _ 2 |2 MeSH
|a Aborted Fetus: radiography
650 _ 2 |2 MeSH
|a Adult
650 _ 2 |2 MeSH
|a Ear: pathology
650 _ 2 |2 MeSH
|a Ear: radiography
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Pelizaeus-Merzbacher Disease: pathology
650 _ 2 |2 MeSH
|a Pelizaeus-Merzbacher Disease: radiography
650 _ 2 |2 MeSH
|a Pregnancy
650 _ 2 |2 MeSH
|a Temporal Bone: pathology
650 _ 2 |2 MeSH
|a Temporal Bone: radiography
650 _ 2 |2 MeSH
|a X-Ray Microtomography
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|a Schwentner, I.
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700 1 _ |0 P:(DE-HGF)0
|a Glueckert, Robert
|b 2
|e Corresponding author
700 1 _ |0 P:(DE-HGF)0
|a Sergi, C.
|b 3
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|a Beckmann, F.
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|a Abraham, I.
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|a Riechelmann, H.
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|a Schrott-Fischer, A.
|b 7
700 1 _ |a Müller, B.
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