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@ARTICLE{Raab:642747,
author = {Raab, Aileen Rebecca and Griesser, Tanja Robin and Rück,
Daniel and Li, Zhuoqing and Zens, Anna and Bruckner, Johanna
R. and Huber, Patrick and Schönhals, Andreas and Szymoniak,
Paulina and Laschat, Sabine},
title = {{S}alt {C}omplexation {D}rives {L}iquid {C}rystalline
{S}elf-{A}ssembly in {C}rown {E}ther–{A}mino {A}cid
{H}ybrids},
reportid = {PUBDB-2025-05596},
year = {2025},
note = {(DFG grant # LA 907/21-1; HU 850/13-1; SCHO 470/26-1) and
DFG (INST 41/897-1 FUGG for 700 MHz NMR, INST 41/1136-1 FUGG
for Orbitrap LC-MS),},
abstract = {Crown ether–amino acid hybrids represent a promising
class of amphiphilic molecules combining ion recognition
with self-assembly capabilities. Despite extensive studies
on their binding properties, the influence of inorganic salt
complexation on their liquid crystalline behaviour remains
underexplored. Here we synthesized amphiphilic [18]-crown-6
derivatives of L-dihydroxyphenylalanine and
tetrahydroisoquinoline analogues, systematically
investigating the effects of alkyl chain length and salt
type on mesophase formation. Complexation with various salts
induced liquid crystalline phases, transitioning from
smectic A to columnar hexagonal structures as anion size and
alkyl chain length increased. Structural analyses and
electron density mapping revealed assembly into charged
superdiscs forming columnar stacks with tunable ion
channels. Broadband dielectric spectroscopy highlighted
differences in molecular mobility and conductivity linked to
molecular design. These findings establish salt complexation
as a key strategy to control self-assembly and ion transport
in crown ether–amino acid hybrids, advancing their
potential in responsive soft materials and ion-conductive
applications},
cin = {CIMMS},
cid = {I:(DE-H253)CIMMS-20211022},
pnm = {632 - Materials – Quantum, Complex and Functional
Materials (POF4-632)},
pid = {G:(DE-HGF)POF4-632},
experiment = {EXP:(DE-MLZ)NOSPEC-20140101},
typ = {PUB:(DE-HGF)25},
doi = {10.26434/chemrxiv-2025-25sz1},
url = {https://bib-pubdb1.desy.de/record/642747},
}