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@ARTICLE{OrtizMahecha:640689,
author = {Ortiz-Mahecha, Carlos and Schwob, Lucas and Leroux,
Juliette and Bari, Sadia and Meissner, Robert and Bande,
Annika},
title = {{X}-ray absorption spectroscopy reveals charge transfer in
π-stacked aromatic amino acids},
journal = {Physical chemistry, chemical physics},
volume = {27},
number = {16},
issn = {1463-9076},
address = {Cambridge},
publisher = {RSC Publ.},
reportid = {PUBDB-2025-04829},
pages = {8202 - 8211},
year = {2025},
abstract = {X-ray absorption spectroscopy (XAS) and quantum mechanical
calculations bear great potential to unravel π stacking
side-chain interaction properties and structure in, e.g.,
proteins. However, core-excited state calculations for
proteins and their associated interpretation for π–π
interactions are challenging due to the complexity of the
non-covalent interactions involved. A theoretical analysis
is developed to decompose the core-to-valence transitions
into their atomic contributions in order to characterize the
π stacking of aromatic amino acids as a function of their
non-covalent distance change. Three models were studied as a
non-covalent mixed dimers of the phenylalanine, tyrosine and
tryptophan amino acids. We found that there are carbon 1s
→ π* charge transfer transitions associated with the
non-covalently paired aromatic amino acids through their
side chains. The atomic-centered contributions to the
electronic transition density quantify the excited state
charge transfer of the pairing amino acid models,
highlighting the π stacking interactions between their
aromatic side chains.},
cin = {FS-BIG},
ddc = {540},
cid = {I:(DE-H253)FS-BIG-20220318},
pnm = {633 - Life Sciences – Building Blocks of Life: Structure
and Function (POF4-633) / AIM, DFG project
G:(GEPRIS)390715994 - EXC 2056: CUI: Advanced Imaging of
Matter (390715994) / DFG project G:(GEPRIS)217133147 - SFB
1073: Kontrolle von Energiewandlung auf atomaren Skalen
(217133147)},
pid = {G:(DE-HGF)POF4-633 / G:(GEPRIS)390715994 /
G:(GEPRIS)217133147},
experiment = {EXP:(DE-MLZ)NOSPEC-20140101 / EXP:(DE-H253)P-P24-20150101},
typ = {PUB:(DE-HGF)16},
doi = {10.1039/D4CP04615C},
url = {https://bib-pubdb1.desy.de/record/640689},
}