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@ARTICLE{Skiba:637942,
      author       = {Skiba, Marvin and Klemeyer, Lars and Guedes, Gabriela and
                      Sun, Xiao and Haas, Sylvio and Cortajarena, Aitziber L. and
                      Koziej, Dorota and Parak, Wolfgang J. and Sanchez-Cano,
                      Carlos},
      title        = {{P}robing the {B}iological {I}dentity of {I}norganic
                      {N}anoparticles with {A}nomalous {S}mall {A}ngle {X}‐{R}ay
                      {S}cattering},
      journal      = {Small},
      volume       = {21},
      number       = {32},
      issn         = {1613-6810},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {PUBDB-2025-03932},
      pages        = {2504135},
      year         = {2025},
      abstract     = {In a biological milieu, nanoparticles (NPs) undergo
                      alterations that go from aggregation or degradation to the
                      adsorption of a corona of proteins. Those changes influence
                      significantly the intrinsic properties and biological
                      capacities of the engineered nanomaterials and need to be
                      fully understood for the successful biomedical use of NPs.
                      Synchrotron anomalous small-angle X-ray scattering (ASAXS)
                      is used to probe the individual small-angle X-ray scattering
                      (SAXS) contributions from the different components of NPs
                      (core, polymeric coating, and protein corona) on several in
                      vitro systems. By applying a model-based fitting approach
                      combined with pair distance distribution analysis, it is
                      possible to investigate whether and to what extent proteins
                      formed a corona around different nanoparticles. The results
                      obtained agree with well-established dynamic light
                      scattering and transmission electron microscopy experiments,
                      confirming the capacity of ASAXS to obtain full information
                      from complex NP samples, and opening for its use in more
                      realistic biological environments.},
      cin          = {DOOR ; HAS-User / FS-PETRA-D},
      ddc          = {620},
      cid          = {I:(DE-H253)HAS-User-20120731 /
                      I:(DE-H253)FS-PETRA-D-20210408},
      pnm          = {633 - Life Sciences – Building Blocks of Life: Structure
                      and Function (POF4-633) / 6G3 - PETRA III (DESY) (POF4-6G3)},
      pid          = {G:(DE-HGF)POF4-633 / G:(DE-HGF)POF4-6G3},
      experiment   = {EXP:(DE-H253)P-P62-20221101},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.1002/smll.202504135},
      url          = {https://bib-pubdb1.desy.de/record/637942},
}