TY  - JOUR
AU  - Seth, Ajit
AU  - Giri, Rajendra P.
AU  - Hayen, Nicholas
AU  - hitaishi, prashant
AU  - Murphy, Bridget M.
AU  - Ghosh, Sajal K.
TI  - Cholesterol modulated assembly of graphene oxide nano-flakes at a phospholipid interface
JO  - Colloids and surfaces / B
VL  - 255
SN  - 0927-7765
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - PUBDB-2025-02347
SP  - 114934 
PY  - 2025
AB  - Cholesterol, a key structural component of mammalian cell membranes, is crucial in stabilizing the membraneand regulating its biophysical properties. Herein, the self-assembly of graphene oxide (GO) around differentlycharged lipid monolayers modulated by cholesterol has been investigated using surface pressure-area isothermsand synchrotron-based X-ray reflectivity. In pristine lipid monolayers, electrostatic interactions control the selfassemblyof GO nano-flakes around the lipid molecules. However, upon the addition of cholesterol, theadsorption and penetration kinetics of GO nano-flakes into the lipid monolayers are drastically amplified, irrespectiveof the ionic nature of lipids. The experimental observations are discussed in terms of interactionsoccurring among GO nano-flakes, phospholipids, and cholesterol molecules.
LB  - PUB:(DE-HGF)16
C6  - pmid:40644792
DO  - DOI:10.1016/j.colsurfb.2025.114934
UR  - https://bib-pubdb1.desy.de/record/633151
ER  -